Category: 246047-72-3

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

246047-72-3, A 50 mL two-necked flask was purged with argon and then the ligand 7q (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After completion of the reaction, silica gel was added to the filtrate after filtration, and the crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain a green solid product 8q. Yield: 59%.

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium An updated downstream synthesis route of 246047-72-3 as follows.

After a 50 mL two-necked flask was purged with argon, a ligand 7b (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 8b in a yield of 79%., 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,246047-72-3

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3,the ruthenium-catalysts compound, it is a common compound, a new synthetic route is introduced below.

After a 50 mL two-necked flask was purged with argon, ligand 5c (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to prepare a sand product. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a yellow-green solid product 6c in a yield of 96%.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, 246047-72-3

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 246047-72-3, its synthesis route is as follows.

A suspension of 100 mg (0.12 mmol) of [RuCl2(PCy3) (ImH2Mes)(phenylmethy- lene)], 12 mg (0.12 mmol) copper chloride and 100 mg (0.12 mmol) 2-phenyl-8-vinyl- quinoline-4-ol in 11 ml methylene chloride was stirred at 400C for 1 h. The reaction mixture was evaporated to dryness and the isolated crude product purified by silica gel chromatography (hexane / ethyl acetat 2:1) to yield 51 mg (61%) of the title compound as green crystals. MS: 711.1 (M+). 1H-NMR (300 MHz, CD2Cl2): 2.32 (s, 12H); 2.41 (s, 6H); 3.90 (s, 4H); 6.12-6.28 (br, IH); 6.80-6.92 (m, 2H); 6.98 (s, 4H); 7.04-7.14 (m, IH); 7.19 (t, J=7.1Hz, IH); 7.29 (d, J=6.9Hz, IH); 7.35 (d, J=7.5Hz, 2H); 7.49 (d, J=7.1Hz, IH); 7.80-8.00 (br, IH); 17.34 (s, IH).

246047-72-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,246047-72-3 ,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/644; (2008); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, and cas is 246047-72-3, its synthesis route is as follows.

Example4 Synthesis of the Complex 3 According to the Invention [0080] The commercially available complex G (1.0 g, 1.18 mmol) was placed in a flask, to which methylene chloride was added (24 ml). This was followed by adding the compound of the formula: (141 mg, 1.17 mmol) and tricyclohexylphosphine (330 mg, 1.18 mmol). The resulting solution was stirred at a temperature of 40 C. for 5 hours. The reaction mixture was introduced at the top of a chromatographic column packed with silica gel (eluent: ethyl acetate/cyclohexane, 0 to 10 vol. %). After evaporating the solvents, the complex 3 was obtained as a green solid (797 mg, 82% yield). The NMR data are consistent with Example 3.

246047-72-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,246047-72-3 ,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Skowerski, Krzysztof; Bieniek, Michal; US2015/158896; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, and cas is 246047-72-3, its synthesis route is as follows.

Under an argon atmosphere a carbene complex of formula 5.II, wherein L represents a NHC ligand of formula 6a.II (153 mg, 0.18 mmol),and anhydrous CuCl (18 mg, 0.18 mmol) were placed in a Schlenck tube. Then dry, deoxygenated CH2C12 (10 ml) was added followed by a solution of compound 2.1 (38 mg, 0.18 mmol) in CH2C12 (4 ml). The resulting suspension was stirred at 30C for 1 h, thereafter it was concentrated in vacuum, and purified by silica-gel column chromatography (cyclohexane / EtOAc 5:2). After removal of solvent and washing with small amount of dry n-pentane complex 1.II, wherein Mes has the meaning of a mesityl group, was obtained as green, microcrystalline solid (100 mg, 83% of yield). Rf = 0.30 (hexane/EtOAc8:2);XH-NMR (500 MHz, CD2Cl2): delta[ppm]= 16.42 (s, 1H), 8.46 (dd, 1H, J = 9.1, 2.5 Hz), 7.80 (d, 1H, J = 2.5 Hz), 7.10 (s, 4H), 6:94 (d, 1H, J = 9.1 Hz), 5.01 (sept, 1H, J = 6.1 Hz), 4.22 (s, 4H), 2.47 (2s, 18H), 1.30 (d, 6H, J = 6.1 Hz); 13C-NMR (125 MHz, CD2Cl2): delta;[ppm]= 289.1, 208.2,156.8, 150.3, 145.0, 143.5, 139.6,139.3,129.8, 124.5,117.2,113.3, 78.2, 52.0, 21.3, 21.2,19.4; IR (KBr): nu [cm-1] = 2924, 2850,1606,1521,1480,1262, 1093, 918,745; MS (ESI): m/z 636 [M-CI]+; HRMS(EI): m/z calculated for C31H37N3O3Ru: [M+.] 671.1255, found 671.1229; Elemental analysis, calculated: (%) for C31H37N3O3Ru (671.63): C 55.44, H 5.55, N 6.26; found: C 55.35; H 5.70, N 6.09.

246047-72-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,246047-72-3 ,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, other downstream synthetic routes, hurry up and to see

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 246047-72-3, its synthesis route is as follows.

In a flame dry Schlenk tube 2nd generation Grubbs catalyst(98 mg, 0.11 mmol), CuCl (12.0 mg, 0.12 mmol) and ligand precursor 7 (35.0 mg, 0.11 mmol) were placed. Then, dry DCM was addedunder atmosphere of argon and a mixture was heated to 30 C. The progress of the reaction was monitored by TLC (c-Hex:EtOAc, 2:1).After 20 min the reaction mixture was cooled down to RT and thesolvent was evaporated. Purification by silica-gel chromatography(c-Hex:EtOAc, 10:1, followed by c-Hex:EtOAc, 3:2) yielded brick-redsolid (48%). A single crystal of compound 11 suitable for X-raydiffraction studies was grown at a temperature of 5 C from atrichloromethane/n-hexane solution. 1H NMR (400 MHz, CD2Cl2): delta= 17.9 (s, 1H, Ru]CHAr), 8.50 (d, 1H, J 12.0, Ar-H), 7.87 (dd, 1H,J 16.0, 8.0, Ar-H), 7.45-6.88 (m, 10H, Ar-H), 4.28-4.04 (m, 4H,CH2 2), 2.67-2.34 (br, 15H, CH3 5), 2.01 (s, 3H, CH3); 13C NMR(125 MHz, CD2Cl2): delta=303.9, 210.9, 142.8, 140.3, 136.8, 134.5, 132.7,130.5, 129.5, 128.7, 128.0, 125.7, 125.0, 123.0, 116.6, 77.5, 52.2, 51.1,20.9, 19.9, 19.8, 18.4, 17.6; IR (film from CH2Cl2): n 2913, 1607,1481, 1414,1258, 1013, 924, 849, 806, 763, 645, 576, 552 cm1; Anal.Calcd. for C34H36BrCl2N4ORu: C, 53.13; H, 4.72; N, 7.29; Found: C,53.81; H, 4.76; N, 7.27, m/z 791.0, [MNa].

246047-72-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,246047-72-3 ,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Szwaczko, Katarzyna; Czelu?niak, Izabela; Grela, Karol; Journal of Organometallic Chemistry; vol. 847; (2017); p. 146 – 153;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3,the ruthenium-catalysts compound, it is a common compound, a new synthetic route is introduced below.

A suspension of 1.00 g (1.18 mmol) of [RuCl2(PCy3)(ImH2Mes)(phenylmethylene)](commercially available from Sigma- Aldrich Inc., St. Louis, USA), 0.13 g (1.30 mmol) of copper chloride and 0.38 g (1.30 mmol) oflambda/-phenyl-2-[((E,Z)-2-propenyl)-phenoxy]- propionamide as a 4:1 mixture ofE/Z-isomers in 75 ml of dichloromethane was stirred for 30 min at 400C. The reaction mixture was evaporated to dryness at 400C/ 10 mbar. The residue was stirred in 75 ml of ethyl acetate for 30 min at room temperature. The dark green suspension was filtered and the filtrate was evaporated to dryness at 40C/10 mbar. The crude title product was purified by silica gel chromatography (cyclohexane/ethyl acetate 4:1) to yield 0.75 g (88% yield) of the title compound as a green powder.MS: 731.1 (M+). Anal, calcd. for C37H4ICl2N3O2Ru ? V3 C6Hi2: C, 61.65; H, 5.97; N, 5.53; Cl, 9.33. Found: C, 61.83; H, 6.71; N, 5.35; Cl, 8.93.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, 246047-72-3

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/124853; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3,the ruthenium-catalysts compound, it is a common compound, a new synthetic route is introduced below.

To a solution of 6e (33.0 mg, 0.05 mmol) in anhydrous CH2Cl2 (6.0 ml) was added 2ndgeneration Grubbs catalyst (39.7 mg, 0.05 mmol) and CuCl (I) (4.6 mg, 0.05 mmol)under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated invacuo, and the residue was purified by column chromatography on silica gel (hexane /CH2Cl2 = 1 / 1) to give 2i (25.2 mg, 46%).Green crystals; mp 116.3-117.0 C; 1H NMR (270 MHz, CDCl3) delta 0.86 (d, J = 6.2 Hz,6H), 2.50 (br s, 18H), 4.23 (s, 4H), 4.45-4.54 (m, 1H), 7.07-7.12 (m, 6H), 7.26-7.54 (m,3H), 7.62 (d, J = 2.2 Hz, 1H), 7.80-7.87 (m, 4H), 16.51 (s, 1H); 19F (466 MHz, CDCl3)delta -80.6 (3F), 109.6 (2F), -121.1 (4F), -121.7 (4F), -122.5 (2F), -125.9 (2F); 13C NMR(68 MHz, CDCl3) delta 15.3, 22.1, 22.7, 66.0, 77.3, 110.3-119.9 (m, C8F17), 123.9, 124.3,124.7, 126.4, 127.3, 127.7, 127.9, 128.2, 129.1, 131.7, 132.8, 133.5, 133.7, 135.8, 136.3,155.8; IR (FT) 2919, 2360, 1605, 1481, 1398, 1242, 1207, 1145, 1109, 1094, 743 cm-1;HRMS (FAB) m/z [M+H]+ calcd for C49H44Cl2F17N2ORu 1172.1689; found 1172.1731.

The chemical industry reduces the impact on the environment during synthesis,246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,I believe this compound will play a more active role in future production and life.

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI