Category: ruthenium-catalysts

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium An updated downstream synthesis route of 246047-72-3 as follows., 246047-72-3

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,6-dimethylphenylimino)methyl]phenol (pKa: 8.85+/- 0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on a chromatography column to give an orange-brown complex. Yield 22%.

246047-72-3, The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Telene SAS; EP2151445; (2010); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

General procedure: The amine (4-CH3-pip, 4-CH2Ph-pip or 4-CH2(OH)-pip; 0.34 mmol) was added to a solution of [RuCl2(PPh3)3] (0.26 mmol; 0.25 g) in acetone (40 mL). The resulting dark green solution was stirred for 2 h at RT. A green precipitate was formed, filtered, washed with methanol and ethyl ether, and then dried in vacuum. Complex 1 (R = H): 75% yield. Analytical data for RuCl2P2NC42H43 are 63.40C, 5.45H, and 1.76% N; found 63.59C, 5.47H, and 1.88% N. FTIR in CsI: 322 cm-1 for nu(Ru-Cl); 3228 cm-1 for nu(N-H). 31P{1H} NMR in CDCl3: 62.7 ppm (s). Complex 2 (R = Ph): 58% yield. Analytical data for RuCl2P2NC48H47 are 66.13C, 5.43H, and 1.61% N; found 66.41C, 5.37H, and 1.72% N. FTIR in CsI: 320 cm-1 for nu(Ru-Cl); 3257 cm-1 for nu(N-H). 31P{1H} NMR in CDCl3: 62.7 ppm (s).

15529-49-4, The synthetic route of 15529-49-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Chaves, Henrique K.; Ferraz, Camila P.; Carvalho Jr., Valdemiro P.; Lima-Neto, Benedito S.; Journal of Molecular Catalysis A: Chemical; vol. 385; (2014); p. 46 – 53;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Ruthenium(III) chloride hydrate, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route. 20759-14-2

(4) Preparation of trans-3′-oxospiro[cyclohexane-1,1′(3’H)-isobenzofuran]-4-carboxylic acid A mixture of 4-hydroxymethylspiro[cyclohexane-1,1′(3’H)-isobenzofuran]-3’one (190 mg), chloroform (2.0 mL), acetonitrile (2.0 mL) and sodium phosphate buffer (pH6.5, 2.0 mL) was cooled to 0 C., to which sodium periodate (612 mg) and ruthenium(III) chloride n-hydrate (10 mg) were added and the mixture was stirred for 30 minutes. The reaction mixture was stirred together with 1N hydrochloric acid (2.0 mL) for 30 minutes and partitioned between water (50 mL) and ethyl acetate (50 mL). The organic layer was washed with saturated saline solution, dried over anhydrous Na2SO4 and then concentrated. The residue was purified by column chromatography on silica gel (chloroform/methanol=100/1) to give the subject compound (98.6 mg).

With the rapid development of chemical substances, we look forward to future research findings about Ruthenium(III) chloride hydrate

Reference£º
Patent; Banyu Pharmaceutical Co., Ltd.; US6803372; (2004); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

50982-12-2, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc.Dichloro(cycloocta-1,5-diene)ruthenium(II), below Introduce a new synthetic route.

Complex C-l was also prepared using [RuCl2(COD)]n as a precursor. Thus, a mixture of [RuCl2(COD)]n (309 mg, 1.103 mmol), PPh3 (289 mg, 1.103 mmol) and ligand Id (248 mg, 1.103 mmol) was stirred in toluene (10 ml) at 115C for 24 h in a KONTES pressure tube. After cooling, the resulting brick colored precipitate was filtered on a filter frit, washed with diethyl ether (3 x 10 ml) and vacuum dried to afford 494 mg of a light pink crude material (Found C, 53.43; H, 5.26; N, 4.08%). Recrystallization from hot THF, filtering and layering with diethyl ether, afforded burgundy crystals (261 mg, 32% yield as a THF solvate). Based on NMR analysis, these crystals represent a THF solvate of complex C-l. The crystals were found to lose solvent based on elemental analysis. Elem. Anal: Calc’d for C3oH35Cl2N2PRuS (658.63): C, 54.71; H, 5.36; N, 4.25%; Found C, 54.37; H, 5.66; N, 3.87%.

50982-12-2 Dichloro(cycloocta-1,5-diene)ruthenium(II) 11000435, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; LOS ALAMOS NATIONAL SECURITY, LLC; DUB, Pavel, A.; GORDON, John, Cameron; WO2015/191505; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium An updated downstream synthesis route of 246047-72-3 as follows.

After a 50 mL two-necked flask was purged with argon, the ligand 3cw (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate after filtration to obtain sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 4cw, yield: 85%.

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is Dichlorotris(triphenylphosphino)ruthenium (II), as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 15529-49-4, its synthesis route is as follows.,15529-49-4

Solid [Ru(PPh3)3Cl2] (200 mg, 0.21 mmol) was added to a methanol solution (30 ml) of H2L1 (153 mg, 0.42 mmol) and NaOAc(35 mg, 0.42 mmol). The mixture was boiled under reflux for 1 h and then cooled to room temperature. The red solid deposited was collected by filtration and dried in air. This material was dissolved in minimum amount of dichloromethane and transferred to a silica gel column packed with dichloromethane. The first yellow band moved with the eluent 1 : 4 mixture of dichloromethane/ n-hexane was discarded. The following red band containing the complex 1 was eluted with a 2 : 3 mixture of dichloromethane/ n-hexane. The red solution thus obtained was evaporated to dryness and the complex was collected as a dark red solid. The yield was 220 mg (78 %).

With the complex challenges of chemical substances, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II)

Reference£º
Article; Nagaraju, Koppanathi; Pal, Samudranil; Inorganica Chimica Acta; vol. 413; (2014); p. 102 – 108;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium This compound has unique chemical properties. The synthetic route is as follows. 246047-72-3

Example 5 Synthesis of the Complex 4 According to the Invention [0081] The commercially available complex G (200 mg, 0.24 mmol) was placed in a flask, to which methylene chloride was added (6 ml). This was followed by adding the compound of the formula: (78 mg, 0.47 mmol) and tricyclohexylphosphine (132 mg, 0.47 mmol). The resulting solution was stirred at a temperature of 40 C. for 1 hour. The reaction mixture was introduced at the top of a chromatographic column packed with silica gel (eluent: ethyl acetate/cyclohexane, 0 to 10 vol. %). After evaporating the solvents, the complex 4 was obtained as a brown solid (104 mg, 50% yield). [0082] 1H NMR (500 MHz, CD2Cl2) delta ppm: 16.42 (s, 1H), 8.00 (dd, J=9.3, 2.7 Hz, 1H), 7.53 (d, J=2.7 Hz, 1H), 7.12 (s, 1H), 7.06 (s, 2H), 6.69 (d, J=9.3 Hz, 1H), 6.22 (s, 1H), 4.07-4.03 (m, 1H), 3.88-3.77 (m, 2H), 3.73-3.67 (m, 1H), 2.64 (s, 3H), 2.56 (s, 3H), 2.51 (s, 3H), 2.39 (s, 3H), 2.27 (s, 3H), 1.64-1.50 (m, 13H), 1.46 (m, 3H), 1.12-0.75 (m, 20H). 13C NMR: (125 MHz, CD2Cl2) delta ppm: 282.23 (d), 220.27, 219.73, 184.63 (d), 145.82, 139.23 (d), 139.08, 138.89, 137.46, 136.76, 136.69, 134.24, 134.00, 130.55, 130.36, 129.41 (d), 125.78, 117.59, 115.27, 52.14 (d), 51.63 (d), 34.52, 32.77, 32.64, 29.40, 28.91, 28.00 (m), 26.90 (d), 22.73, 21.34, 21.01, 19.41, 18.63, 18.53, 17.10, 14.21.

With the rapid development of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

Reference£º
Patent; Skowerski, Krzysztof; Bieniek, Michal; US2015/158896; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Adding a certain compound to certain chemical reactions, such as: 246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 246047-72-3, 246047-72-3

Grubbs second generation catalyst (100 mg, 0.118 mmol) andacrylonitrile (25 mg, 0.472 mmol) were stirred in toluene (5 mL) for15 h at room temperature. After removal of volatiles by evacuation,the brown powder was washed with pentane (3 ¡Á 5 mL) and driedunder vacuum, affording 7-CN as a brown solid in a 80% yield

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Article; Vancompernolle, Tom; Vignon, Paul; Trivelli, Xavier; Mortreux, Andre; Gauvin, Regis M.; Catalysis Communications; vol. 77; (2016); p. 75 – 78;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, Adding a certain compound to certain chemical reactions, such as: 246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 246047-72-3

Under an argon atmosphere a carbene complex of formula 5.II, wherein L represents a NHC ligand of formula 6a.II (153 mg, 0.18 mmol),and anhydrous CuCl (18 mg, 0.18 mmol) were placed in a Schlenck tube. Then dry, deoxygenated CH2C12 (10 ml) was added followed by a solution of compound 2.1 (38 mg, 0.18 mmol) in CH2C12 (4 ml). The resulting suspension was stirred at 30C for 1 h, thereafter it was concentrated in vacuum, and purified by silica-gel column chromatography (cyclohexane / EtOAc 5:2). After removal of solvent and washing with small amount of dry n-pentane complex 1.II, wherein Mes has the meaning of a mesityl group, was obtained as green, microcrystalline solid (100 mg, 83% of yield). Rf = 0.30 (hexane/EtOAc8:2);XH-NMR (500 MHz, CD2Cl2): delta[ppm]= 16.42 (s, 1H), 8.46 (dd, 1H, J = 9.1, 2.5 Hz), 7.80 (d, 1H, J = 2.5 Hz), 7.10 (s, 4H), 6:94 (d, 1H, J = 9.1 Hz), 5.01 (sept, 1H, J = 6.1 Hz), 4.22 (s, 4H), 2.47 (2s, 18H), 1.30 (d, 6H, J = 6.1 Hz); 13C-NMR (125 MHz, CD2Cl2): delta;[ppm]= 289.1, 208.2,156.8, 150.3, 145.0, 143.5, 139.6,139.3,129.8, 124.5,117.2,113.3, 78.2, 52.0, 21.3, 21.2,19.4; IR (KBr): nu [cm-1] = 2924, 2850,1606,1521,1480,1262, 1093, 918,745; MS (ESI): m/z 636 [M-CI]+; HRMS(EI): m/z calculated for C31H37N3O3Ru: [M+.] 671.1255, found 671.1229; Elemental analysis, calculated: (%) for C31H37N3O3Ru (671.63): C 55.44, H 5.55, N 6.26; found: C 55.35; H 5.70, N 6.09., 246047-72-3

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.50982-12-2, Dichloro(cycloocta-1,5-diene)ruthenium(II) it is a common compound, a new synthetic route is introduced below., 50982-12-2

50982-12-2, The catalyst precursor, preferably [RuCI2(COD)]m (1 eq.) (COD = cis,cis-cycloocta-1 ,5 diene), 1 ,4-bis(diphenylphosphino)butane (1.0-1 .2 eq., preferably 1.0 eq.) and 2-picolylamine (1 .0-1.4 eq., preferably 1.225 eq.) were dissolved in one of the above mentioned solvents, preferably methyl isobutylketone (10-20 ml/g Ru-precursor, preferably 20 ml/g). The mixture was heated to reflux for 3 – 5 hours and then cooled to ambient temperature. The solid precipitate was filtered off and washed with the same solvent that was used for the reaction. A person skilled in the art can determine the cis-/trans- isomeric ratio by NMR. The diastereomeric ratios generated by this method are usually in the range of d.r. (diastereomeric ratio) >98% towards the cis isomer. The same results can be achieved starting with [RuCI2(dmso-KS)3(dmso-KO)], [RuCI2(dmso-KS)4]or [RuCI2(bicyclo[2.2.1 ]hepta- 2,5-diene)]m as precursor

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.

Reference£º
Patent; SYNGENTA PARTICIPATIONS AG; LOTHSCHUETZ, Christian; SAINT-DIZIER, Alexandre Christian; WO2014/166777; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI