Category: ruthenium-catalysts

As a common heterocyclic compound, it belong ruthenium-catalysts compound,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,246047-72-3,Molecular formula: C46H65Cl2N2PRu,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

A 50 mL two-necked flask was purged with argon and the ligands 3cy (10mmol), CuCl (30mmol, 3eq) and 30mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand after filtration. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain 4cy green solid product in a yield of 70%.

With the synthetic route has been constantly updated, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belong ruthenium-catalysts compound,Dichlorotris(triphenylphosphino)ruthenium (II),15529-49-4,Molecular formula: C54H45Cl2P3Ru,mainly used in chemical industry, its synthesis route is as follows.,15529-49-4

RuCl2(PPh3)3(480 mg, 0.5 mmol) was placed in a 25 mL flask filled with argon. THF(12.5 mL) and (R,R)-DPEN (127 mg, 0.6 mmol) were then added. The mixturewas degassed and stirred under argon at 25 oC for 6 h. After removalof turbidity by filtration, n-hexane (30 mL) was added, and a light yellowsolid was obtained. The supernatant was removed and the resulting solid wasdried under reduced pressure to give analytically pure 1f (442 mg, 97% yield). 2.1. RuCl2(R,R)-DPEN(PPh3)2 1f1H NMR (300MHz, C6D6, ppm), delta: 7.95-7.92 (m,12H), 6.97-6.95 (m, 18H), 6.74 (br, 10H), 4.61-4.4.59(m, 2H), 4.12-4.09 (m, 2H), 3.59-3.56 (m, 2H); 31P NMR (121MHz, C6D6, ppm), delta: 45.7.

With the synthetic route has been constantly updated, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II),belong ruthenium-catalysts compound

Reference£º
Article; Li, Xuefeng; Ma, Yaping; Xing, Zhikui; Tang, Ning; Zhu, Jin; Deng, Jingen; Tetrahedron Letters; vol. 55; 29; (2014); p. 3868 – 3872;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belong ruthenium-catalysts compound,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,246047-72-3,Molecular formula: C46H65Cl2N2PRu,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

With the synthetic route has been constantly updated, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO482,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

Example 5 – Synthesis of the complex 4 according to the invention The commercially available complex G (200 mg, 0.24 mmol) was placed in a flask, to which methylene chloride was added (6 ml). This was followed by adding the compound of the formula: (78 mg, 0.47 mmol) and tricyclohexylphosphine (132 mg, 0.47 mmol). The resulting solution was stirred at a temperature of 40C for 1 hour. The reaction mixture was introduced at the top of a chromatographic column packed with silica gel (eluent: ethyl acetate/cyclohexane, 0 to 10 vol.%). After evaporating the solvents, the complex 4 was obtained as a brown solid (104 mg, 50% yield). 4 H NMR (500 MHz, CD2CI2) delta ppm: 16.42 (s, 1H), 8.00 (dd, J = 9.3, 2.7 Hz, 1H), 7.53 (d, J = 2.1 Hz, 1H), 7.12 (s, 1H), 7.06 (s, 2H), 6.69 (d, J = 9.3 Hz, 1H), 6.22 (s, 1H), 4.07- 4.03 (m, 1H), 3.88-3.77 (m, 2H), 3.73-3.67 (m, 1H) , 2.64 (s, 3H), 2.56 (s, 3H), 2.51 (s, 3H), 2.39 (s, 3H), 2.27 (s, 3H), 1.64-1.50 (m, 13H), 1.46 (m, 3H), 1.12-0.75 (m, 20H). 13C NMR: (125 MHz, CD2CI2) delta ppm: 282.23 (d), 220.27, 219.73, 184.63 (d), 145.82, 139.23 (d), 139.08, 138.89, 137.46, 136.76, 136.69, 134.24, 134.00, 130.55, 130.36, 129.41 (d), 125.78, 117.59, 115.27, 52.14 (d), 51.63 (d), 34.52, 32.77, 32.64, 29.40, 28.91, 28.00 (m), 26.90 (d), 22.73, 21.34, 21.01, 19.41, 18.63, 18.53, 17.10, 14.21.

With the synthetic route has been constantly updated, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

Reference£º
Patent; APEIRON SYNTHESIS S.A.; SKOWERSKI, Krzysztof; BIENIEK, Micha?; WO2014/16422; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO465,mainly used in chemical industry, its synthesis route is as follows.,15529-49-4

General procedure: The reaction of 2,6-diacetylpyridine mono(4-methoxyphenylthiosemicarbazone) ligand, HL1, prepared as described in reference 35, with RuCl2(PPh3)3 in 1:1M ratios was carried out, in presence of Et3N, in degassed toluene for 3hat room temperature under nitrogen atmosphere. The resulting brown solution was filtered and evaporated to dryness. The solid residue was washed with pentane and dried in vacuo. Further purification by recrystallization from DMSO led to single crystals which were studied by X-ray diffraction techniques.

With the synthetic route has been constantly updated, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II),belong ruthenium-catalysts compound

Reference£º
Article; Matesanz, Ana I.; Hernandez, Carolina; Perles, Josefina; Souza, Pilar; Journal of Organometallic Chemistry; vol. 804; (2016); p. 13 – 17;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

After a 50 mL two-necked flask was purged with argon, the ligand 7k (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were successively added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After completion of the reaction, silica gel was added to the filtrate after filtration, and the crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain a green solid product 8k in a yield of 77%., 246047-72-3

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

Example 8: Dichloro[(N-(2-(diphenylphosphino)benzyl)-2-(ethylthio)ethanamine)(triphenylphosphine)]ruthenium(ll) 8 (8) Under argon 2-(methylthio)benzaldehyde (0.33 g, 2.18 mmol) is added to a solution of 2- (di-phenylphosphino)ethanamine (0.50 g, 2.18 mmol) in methanol (6 ml). After stirring for 42 h at 75 C the reaction mixture is cooled to room temperature and evaporated under vacuo. SNP-ligand 2-(diphenylphosphino)-N-(2-(methylthio)benzylidene)ethanamine is obtained as a light-brown solid (0.66 g, 84%). Analytical data: 1H-NMR (500 MHz, CDCl3): 8.74 (s, 1H), 7.79 (dd, 7=1.58, 7.88, 1H), 7.52-7.48 (m, 4H), 7.39- 5 7.32 (m, 8H), 7.21 (m, 1H), 3.80 (m, 2H), 2.53 (m, 2H), 2.48 (s, 3H). 13C-NMR (500 MHz, CDCl3): 159.37, 138.34, 134.24, 132.88, 132.74, 130.78, 130.66, 128.59, 128.49, 128.44, 128.25, 127.28, 125.50, 58.58, 29.99, 16.90. 31P-NMR (500 MHz, CDCl3): -19.04 (s, 1P). GC/MS: 363 (2%, M+), 348 (2%, [M-15]+), 320 (100%, [M-43]+), 288 (10%), 214 (12%), 183 (39%), 121 (20%), 108 (42%). Under argon dichlorotris(triphenylphosphine)ruthenium(ll) (0.53 g, 0.55 mmol) is added to a solution of 2-(diphenylphosphino)-N-(2-(methylthio)benzylidene)ethanamine (0.20 g, 0.55 mmol) in toluene (15 ml). After stirring for 20 h at 110 C the reaction mixture is cooled to room temperature and evaporated under vacuo to a volume of 5 ml. To this red suspension hexane (20 ml) is added. After stirring for 15 min the suspension is filtered and 15 washed with hexane (4 ml). The red filter cake is dried under vacuo for 19 h and then suspended in diethyl ether (6 ml). The suspension is filtered, washed with diethyl ether (4 x 4 ml) and the filter cake is dried under vacuo. Complex 8 is obtained as a light-red solid (0.29 g, 67%). Analytical data: 1H-NMR (400 MHz, CDCl3): 8.78 (d, 7=8.84, 1H), 8.33 (m, 1H), 7.70 (m, 3H), 7.54-7.06 (m, 20 25H), 4.59 (m, 1H), 4.53 (m, 1H), 2.55 (m, 2H), 1.83 (d, 7=2.53, 3H). 31P-NMR (500 MHz, CDCl3): 40.62 (d, 7=32.27, IP), 36.72 (d, 7=32.37, IP). MS (ESI): 797.18 (62%, M+), 762.12 (100%, [M-Cl]+).

15529-49-4, 15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; GIVAUDAN SA; GEISSER, Roger Wilhelm; OETIKER, Juerg Daniel; SCHROeDER, Fridtjof; WO2015/110515; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,246047-72-3

Complex 1 (2.0 grams) was dissolved in toluene (10 mL), and 4-dimethylaminopyridine (1.18 grams, 4 mol equivalents) was added. The reaction flask was purged with argon and the reaction mixture was stirred for approximately 12 hours at about 20 C. to about 25 C. during which time a color change from dark purple to light green was observed. The reaction mixture was transferred into 75 mL of cold (about 0 C.) pentane, and a light green solid precipitated. The precipitate was filtered, washed with 420 mL of cold pentane, and dried under vacuum to afford (IMesH2)(C7H10N2)2(Cl)2Ru-CHPh 10 as a light green powder (1.9 gram, 99% yield). [00127] 1H NMR (500 MHz, CD2Cl2): d19.10 (s, 1H, CHPh), 8.18 (d, 2H, pyridine CH, JHH=6.5 Hz), 7.64 (d, 2H, ortho CH, JHH=7.5 Hz), 7.48 (t, 11H, para CH, JHH=7.0 Hz), 7.38 (d, 2H, pyridine CH, JHH=6.5 Hz), 7.08 (t, 2H, meta CH, JHH=7.5 Hz), 7.00 (br. s, 2H, Mes CH), 6.77 (br. s, 2H, Mes CH), 6.49 (d, 2H, pyridine CH, JHH=6.0 Hz), 6.15 (d, 2H, pyridine CH, JHH=7.0 Hz), 4.07 (br. d, 4H, NCH2CH2N), 2.98 (s, 6H, pyridine CH3), 2.88 (s, 6H, pyridine CH3), 2.61-2.21 (multiple peaks, 18H, Mes CH3).

With the synthetic route has been constantly updated, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

Reference£º
Patent; California Institute of Technology; Cymetech, LLP; US6759537; (2004); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

RuCl2(PPh3)3 (1 g, 1 .04 mmol) and the ligand of formula (IVg) (obtained from Example 1 ) (231 .4 mg, 1 .1 mmol) were placed in a 25 mL Schlenk tube under argon atmosphere, and dissolved in dry diglyme (2 mL). The reaction mixture was heated to 165C for 2 h, allowed to cool down to room temperature and stored at -18C to precipitate further overnight. Cold Et2O (2 mL) was added while cooling with a dry ice//so-propa- nol bath. The precipitate was filtrated by cannula, and washed with Et2O (5 times 2 mL). The orange powder was dried in vacuo, affording 530 mg (79%) of Ru(6-MeNN- SEt)(PP i3)Cl2 as an orange powder. An equilibrium of two conformations of Ru(6- MeNNSEt)(PPh3)Cl2 are existent in solution, delivering a doubled set of signals in NMR. For 1H-NMR only data of the major conformation is given due to overlapping signals. 1H-NMR (300 MHz, CD2CI2): delta 7.67-7.16 (m, 17H, CHarom), 7.01 (d, 1 H, J = 7.8, CHarom), 5.65 (m, 2H), 4.47 (m, 1 H), 3.5 (m, 1 H), 3.34 (m, 1 H), 3.22 (d, 1 H, J = 1 1 .1 ), 2.98 (m, 1 H), 2.59 (m, 1 H), 1 .53 (m, 2H), 0.87 (t, 3H, J = 7.5) ppm. 31P-NMR (122 MHz, CD2CI2): delta 48.8, 45.8 ppm. HRMS (ESI+): calculated for C29H32CI2N2PRUS (M+H): 644.0518; found 644.0518 (M+H), 667.0412 (M+Na)

15529-49-4, The synthetic route of 15529-49-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; DSM IP ASSETS B.V.; BELLER, Matthias; BONRATH, Werner; DE VRIES, Johannes, Gerardus; FAN, Yuting; HUeBNER, Sandra; LEFORT, Laurent; MEDLOCK, Jonathan, Alan; PUYLAERT, Pim; VAN HECK, Richard; (65 pag.)WO2017/194662; (2017); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI