Category: ruthenium-catalysts

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 6e (33.0 mg, 0.05 mmol) in anhydrous CH2Cl2 (6.0 ml) was added 2ndgeneration Grubbs catalyst (39.7 mg, 0.05 mmol) and CuCl (I) (4.6 mg, 0.05 mmol)under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated invacuo, and the residue was purified by column chromatography on silica gel (hexane /CH2Cl2 = 1 / 1) to give 2i (25.2 mg, 46%).Green crystals; mp 116.3-117.0 C; 1H NMR (270 MHz, CDCl3) delta 0.86 (d, J = 6.2 Hz,6H), 2.50 (br s, 18H), 4.23 (s, 4H), 4.45-4.54 (m, 1H), 7.07-7.12 (m, 6H), 7.26-7.54 (m,3H), 7.62 (d, J = 2.2 Hz, 1H), 7.80-7.87 (m, 4H), 16.51 (s, 1H); 19F (466 MHz, CDCl3)delta -80.6 (3F), 109.6 (2F), -121.1 (4F), -121.7 (4F), -122.5 (2F), -125.9 (2F); 13C NMR(68 MHz, CDCl3) delta 15.3, 22.1, 22.7, 66.0, 77.3, 110.3-119.9 (m, C8F17), 123.9, 124.3,124.7, 126.4, 127.3, 127.7, 127.9, 128.2, 129.1, 131.7, 132.8, 133.5, 133.7, 135.8, 136.3,155.8; IR (FT) 2919, 2360, 1605, 1481, 1398, 1242, 1207, 1145, 1109, 1094, 743 cm-1;HRMS (FAB) m/z [M+H]+ calcd for C49H44Cl2F17N2ORu 1172.1689; found 1172.1731.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,6-dimethylphenylimino)methyl]phenol (pKa: 8.85+/-0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on a chromatography column to give an orange-brown complex. Yield 22%.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Telene S.A.S.; US2011/65925; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50982-12-2,Dichloro(cycloocta-1,5-diene)ruthenium(II),as a common compound, the synthetic route is as follows.

b) A brown suspension of RuCl2(1,5-cyclooctadiene) (560 mg; 2 mmol), 0.6 ml of 1,8-diazobicyclo[5.4.0]undec-7-ene (DBU) and 1.18 g of tricyclohexylphosphine in 60 ml of isopropanol was stirred at 80 C. for 2 hours. 60 ml of toluene was added to the resulting brick-red suspension and the mixture was stirred at 80 C. for a further 90 minutes and cooled to -10 C. After addition of 0.55 ml of trimethylsilylacetylene, 10 ml of 2 M HCl solution in diethyl ether were added and the mixture was subsequently stirred for 5 minutes. The mixture was warmed while stirring to 0 C. and stirred for 45 minutes. After evaporation at 0 C. in a high vacuum, the residue was stirred with cold MeOH. The resulting violet powder was washed with cold methanol and dried under reduced pressure. Yield 1.40 g (92%).

50982-12-2 Dichloro(cycloocta-1,5-diene)ruthenium(II) 11000435, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; Evonik Degussa GmbH; US2011/40099; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a 3 L, 3-neck round bottom flask were added C959 (100.0 g, 104.2 mmol), 1,1- diphenyl-2-propyn-1-ol (24.9 g, 119.8 mmol), and triphenylphosphine (27.3 g, 104.2 mmol) under air. The flask was equipped with a thermocouple and rubber suba-seal septum and then it was placed under Ar using Schlenk technique. The reagents and products of this reaction are highly air sensitive in solution. A 1 L addition funnel was attached to the flask under a flow of Ar. To the addition funnel were added (2-Me)THF (1 L) and 4 M HC1 (25.6 mL, 104.2 mmol) in dioxane using Schlenk technique. The solution was added over 10 minutes at room temperature with stirring. Another 0.75 L (2-Me)THF were added directly to the flask. The addition funnel was replaced with a glass stopper under a flow of Ar and the flask was lowered into a pre-heated oil bath at 65 C. The reaction was monitored by 31P NMR. When conversion was deemed to be complete, the reaction flask was removed from the oil bath and hot filtered via cannula transfer through a celite pad (in an evacuated Schlenk filter) into a Schlenk flask. Approximately 85% (2- Me)THF was removed at room temperature (water bath) under vacuum. The resulting slurry was cooled to 0 C then filtered on a coarse glass frit under air. The solid was washed quickly with 3×50 mL portions of 0 C (2-Me)THF followed by hexanes (200 mL) (r.t.) and 2-propanol (100 mL). The solid from the frit was re-slurred with hexanes (200 mL) and filtered again. The solid was air-dried until no condensation was seen on the outside of the glass frit, then transferred to a 200 mL round bottom flask and dried under high vacuum overnight. The final ?H NMR andNIVIR in CDC13 indicate that the complex is a 1:1 adduct of (PPh3)2Ru(Phlnd)C12, and (2- Me)THF, C973, for a final molecular weight of 973 g/mol. Yield = 74.1 g (73%). 1H NMR (400 MFIz in CDC13 at r.t.): = 7.2-7.6 (overlapping CDC13 andaromatics), 7.07 (d, md, 1H), 6.62 (t, md, 1H), 6.43 (s, md, 1H), 3.92 (m, (2-Me)THF, 2H), 3.70(m, (2-Me)THF, 1H), 1.88-1.98 (overlapping m, (2-Me)THF, 3H), 1.41 (m, (2-Me)THF, 1H), 1.23(d, (2-Me)THF, 3H).

As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; JOHNS, Adam, M.; HERRON, Jessica, R.; PEDERSON, Richard, L.; FIAMENGO, Bryan, A.; BEERMAN, Jennifer, A.; LIN, Tzu-Pin; CHU, Crystal, K.; GRUBBS, Robert, H.; (104 pag.)WO2018/75479; (2018); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.203714-71-0,Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II),as a common compound, the synthetic route is as follows.

NHC ligand precursor 10 (156 mg, .3 mmol), KOz-Bu(F g) (66 mg, .3 mmol), and ruthenium complex 11 (132 mg, .22 mmol) were all combined in toluene in a glove box. The flask was removed and stirred at 60 0C for 18 hours in a fume hood. The reaction mixture was then directly purified by flash column chromatography (5% Et2theta/Hexanes, run 2 times) to yield catalyst 12 (34 mg, 20%) as a green oil. The catalyst was then lyophilized from benzene to give a pale green solid. It should be noted that by 1H NMR the conversion to 12 is 50%. 1H NMR (300 MHz, CDCl3) delta 16.91 (IH, s), 8.14-8.13 (2H, m), 7.73 (2H, m), 7.64 (IH, m), 7.52 (IH, m), 7.06-6.92 (2H, m), 6.62 (IH, t, J = 7.5 Hz), 6.31 (IH, d, J – 8.4 Hz), 4.47 (IH, quint, J = 6 Hz), 3.51 (4H, s), 1.51 (18H, s), 1.35 (6H, d, J = 6 Hz), 1.24 (18H, s); HRMS (EI+) calc for C4IH58N2OCl2Ru 766.2970. Found 766.3007. Fig. 4 depicts the single crystal X-ray structure was obtained for catalyst 12.

The synthetic route of 203714-71-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

After a 50 mL two-necked flask was purged with argon, the ligand 3ch (10 mmol), 30 mL of CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain a green solid product 4ch, yield: 74%.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under argon dichlorotris(triphenylphosphine)ruthenium(II) (0.53 g, 0.55 mmol) is added to a solution of 2-(diphenylphosphino)-N-(2-(methylthio)benzylidene)ethanamine (0.20 g, 0.55 mmol) in toluene (15 ml). After stirring for 20 h at 110 C. the reaction mixture is cooled to room temperature and evaporated under vacuo to a volume of 5 ml. To this red suspension hexane (20 ml) is added. After stirring for 15 min the suspension is filtered and washed with hexane (4 ml). The red filter cake is dried under vacuo for 19 h and then suspended in diethyl ether (6 ml). The suspension is filtered, washed with diethyl ether (4¡Á4 ml) and the filter cake is dried under vacuo. Complex 8 is obtained as a light-red solid (0.29 g, 67%). Analytical data: 1H-NMR (400 MHz, CDCl3): 8.78 (d, J=8.84, 1H), 8.33 (m, 1H), 7.70 (m, 3H), 7.54-7.06 (m, 25H), 4.59 (m, 1H), 4.53 (m, 1H), 2.55 (m, 2H), 1.83 (d, J=2.53, 3H). 31P-NMR (500 MHz, CDCl3): 40.62 (d, J=32.27, 1P), 36.72 (d, J=32.37, 1P). MS (ESI): 797.18 (62%, M+), 762.12 (100%, [M-Cl]+).

As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Patent; GIVAUDAN SA; GEISSER, Roger Wilhelm; OETIKER, Juerg Daniel; SCHROeDER, Fridtjof; (17 pag.)US2016/326199; (2016); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

301224-40-8, (1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A further example of a synthesis producing an NHC containing cis complex is shown below. [0088] HII (200 mg) and P(OiPr)3 (5 eq) were stirred in for 72 h. The crude 65 was recrystallised from DCM/pentane. [0089] 1H (400 MHz, 298K): 16.05 (d, 1H, J=35.3 Hz, C?CH), 10.24 (d, 1H, J=9.7 Hz, Ph-H), 6.87-6.83 (m, 2H, Ph-H), 6.78 (s, 1H, Ph-H), 6.61 (s, 1H, Ph-H), 6.19-6.16 (m, 2H, Ph-H), 4.67 (brs, 2H, PO-CH-CH3), 4.09-4.06 (m, 1H, Ph-O-CH-CH3), 4.04 (brs, 1H, PO-CH-CH3), 3.43-3.40 (m, 1H), 3.16-3.02 (m, 3H), 2.89 (s, 3H, Mes-CH3), 2.58 (s, 3H, CH3), 2.46 (s, 3H, CH3), 2.42 (s, 3H, CH3), 2.18 (s, 3H, CH3), 1.92 (s, 3H, CH3), 1.48-0.80 (m, 24H, PO-CH-CH3). [0090] 31P{1H} (121.49 MHz, 298K): 128.7 (s)

As the paragraph descriping shows that 301224-40-8 is playing an increasingly important role.

Reference£º
Patent; University Court of the University of St. Andrews; Cazin, Catherine; US2014/228563; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

Step 4: (PPh^2CI2Ru(3-2-methylphenyl-5-methylphenyl-inden-1 -ylidene) (1 D): (PPh3)3RuCl2 (1 eq., 0.575 g, 0.6 mmol) and 1 ,1 -bis-2-methylphenyl-prop-2-yn-1-ol (compound C, 1.5 eq., 0.213 g, 0.9 mmol) were added in 4 ml HCI/dioxane solution (0.15 mol/l). The solution was heated to 90C for 3 hour, after which the solvent was removed under vacuum. Hexane (20 ml) was added to the flask and the solid was ultrasonically removed from the wall. The resulting suspension was filtered and washed two times using hexane (5 ml). The remaining solvent was evaporated affording a red-brown powder; 0.52 g (Yield: 95 %). The product was characterized by NMR spectra H and 3 P. H NMR (300 MHz, CDCI3, TMS): delta 7.56 (dd, 1 1 H), 7.37 (t, 6 H), 7.21 -7.31 (m, 13 H), 7.09 (tetra, 3 H), 6.95 (t, 3 H), 6.47 (t, 1 H), 6.14 (s, 1 H), 2.20 (s, 3 H), 1 .66 (s, 3 H). 3 P NMR (121.49 MHz, CDCI3): delta 29.33.

As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Patent; GUANG MING INNOVATION COMPANY (WUHAN); W.C. VERPOORT, Francis; (69 pag.)WO2016/242; (2016); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

(PPh3)3RuCI2 (1 eq., 0.575 g, 0.6 mmol) and 1-t-butyl-1-phenyl-prop-2-yn-1-ol (compound B, 1.5 eq., 0.17 g, 0.9 mmol) were added in 4 ml HCI/dioxane solution (0.15 mol/l). The solution was heated to 90C for 3 hour, after which the solvent was removed under vacuum. Hexane (20 ml) was added to the flask and the solid was ultrasonically removed from the wall. The resulting suspension was filtered and washed two times using hexane (5 ml). The remaining solvent was evaporated affording a red-brown powder; 0.48 g (Yield: 92 %). The product was characterized by NMR spectra 31P.31P NMR (121.49 MHz, CDCI3): 628.76.Example 4: Synthesis of (PPh3)2CI2Ru(3-naphtyl-inden-1-ylidene)

15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; GUANG MING INNOVATION COMPANY (WUHAN); W.C. VERPOORT, Francis; YU, Baoyi; WO2014/108071; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI