Tag: M.W:100-200

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Conjugation in unsaturated systems containing hetero atoms, II. Refined treatment of isoxazole, the phenylisoxazoles, and the benzisoxazoles》. Authors are Berthier, Gaston; Del Re, Giuseppe.The article about the compound:1,2-Benzisoxazolecas:271-95-4,SMILESS:C12=CC=CC=C1ON=C2).Name: 1,2-Benzisoxazole. Through the article, more information about this compound (cas:271-95-4) is conveyed.

cf. CA 57, 12456e. A refined semi-empirical study of the π-systems of isoxazole, phenylisoxazole, and benzisoxazole has been carried out. The purpose of this study was (a) to see how the results previously obtained by the Hueckel method were affected by the inclusion of antisymmetrization and long-range effects, and (b) to ascertain to what extent the criteria and definitions used in Part I for interpreting the results could be considered to be valid in more complicated treatments. As concerns (a), the new results are encouraging for they just show a slight improvement of the good agreement with experimental data already found with the Hueckel method. The refined treatment sheds more light on the importance of mutual polarization in the conjugation of different units. As concerns (b), the use of the refined method has led to a revision of the concept and definition of interaction energy, introduced in Part I to measure the interaction of two π-systems. One can define an “”extra-delocalization energy”” and a “”π-dissociation energy””; the values of the latter quantity are in agreement with the expected order of stability of the combined isoxazole-benzene systems; those of the former appear to be more strictly related to polarization effects. Together with the other results, this suggests that definitions and criteria, valid beyond the limits of the numerical results can be obtained, but a test of them by a refined scheme is essential to ensure that special simplifying features of the original method do not lead to ambiguities. It is concluded that a semiempirical treatment of the Hueckel type can be both a sufficient tool for the chemist and, under the above conditions, a scheme within which quite sound and lasting analyses of fact can be performed.

From this literature《Conjugation in unsaturated systems containing hetero atoms, II. Refined treatment of isoxazole, the phenylisoxazoles, and the benzisoxazoles》,we know some information about this compound(271-95-4)Name: 1,2-Benzisoxazole, but this is not all information, there are many literatures related to this compound(271-95-4).

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Electric Literature of C7H5NO. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,2-Benzisoxazole, is researched, Molecular C7H5NO, CAS is 271-95-4, about Gallium(III) triflate-catalyzed dehydration of aldoximes. Author is Yan, Ping; Batamack, Patrice; Prakash, G. K. Surya; Olah, George A..

Gallium triflate catalyzed dehydration of aldoximes to nitriles is described in good to excellent yields. Good catalytic and dehydrating capabilities of gallium triflate are demonstrated through this dehydration reaction.

From this literature《Gallium(III) triflate-catalyzed dehydration of aldoximes》,we know some information about this compound(271-95-4)Electric Literature of C7H5NO, but this is not all information, there are many literatures related to this compound(271-95-4).

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Ring openings with benz-α,β-isoöxazoles. II》. Authors are Lindemann, Hans; Cissee, Hans.The article about the compound:1,2-Benzisoxazolecas:271-95-4,SMILESS:C12=CC=CC=C1ON=C2).Name: 1,2-Benzisoxazole. Through the article, more information about this compound (cas:271-95-4) is conveyed.

cf. C. A. 23, 2973. Me 6-nitroindoxazene-3-carboxylate is reduced by SnCl2 and HCl to the 6-NH2 derivative, yellow, m. 206° (Ac derivative, m. 210°; di-Ac derivative, m. 130°), which by hydrolysis with H2SO4 gives 6-aminoindoxazene-3-carboxylic acid (I), decomposes 160° with the formation of 4,2-H2N(HO)C6H3CN, m. 182° (Ac derivative, decomposes 260-80°). The Et ester of I, m. 147° (Ac derivative, m. 186-7°), with N2H4.H2O gives the hydrazide, yellow, m. 218°, of 6-acetamidoindoxazene-3-carboxylic acid, transformed by HNO2 into the corresponding aside, m. 155° (decomposition); boiling the latter with the appropriate alc. gives the Pr, Bu and iso-Am esters of 6-acetamidoindoxazene-3-carbamic acid, m. 205, 248 and 215° (decomposition), resp. Boiling the azide with dilute AcOH gives 3-amino-6-acetamidoindoxazene, m. 222° (di-Ac derivative, m. 256°; this by warming with 2 N NaOH passes into 3-o-hydroxy-p-acetamidophenyl-5-methyl-1,2,4,-oxdiazole, m. 210°, also obtained by reducing with SnCl2 and HCl the analogous nitrooxdiazole), and either from the hydrolysis of this compound with dilute H2SO4, or by reduction of 6-nirto-3-aminoindoxazine with SnCl2 3,6-diamidoindoxazene, m. 141°, was obtained. 3-Amino-6-acetamidoindoxazene and HNO2 give the 3-HO derivative, m. 160-5° (decomposition); heating with HCO2H gives 2-hydroxy-4-acetamidobenzohydroxamic acid, m. 218°. The last 2 compounds, warmed with EtCO2H or (EtCO)2O, resp., give 2-hydroxy-4-acetamidobenzopropionylhydroxamic acid, m. 194°, which gives with 2 N NaOH 6-acetamido-2-benzoxazolone, m. 320°. Me 6-chloroindoxazene-3-carboxylate, m. 124°, from the NH2 derivative through the Sandmeyer reaction, with 2 N NaOH gives, on long standing, the free acid, decomposes 171°, with remelting above 300°. Either the acid or ester, boiled with 2 N NaOH, gives 4-chloro-2-hydroxybenzonitrile, m. 155° and forming at 180-200° a cyaphenin derivative The above ester with N2H4 in EtOH gives the hydrazide of 6-chloroindoxazene-3-carboxylic acid, decomposes 192°; HNO2 transforms this into the corresponding aside, m. 142° (decomposition), which in turn is converted by warning with AcOH into bis-[6-chloro-3-indoxazenyl]urea, m. 260°, while boiling Ac2O gives 6-chloro-3-acetamidoindoxazene, m. 186° (the free amine m. 135°), transformed by warming with 2 N NaOH into 3-o-hydroxy-p-chlorophenyl-5-methyl-1,2,4-oxdiazole, m. 79°. Me indoxazene-3-carboxylate, m. 69°; free acid, m. 140-1°; hydrazide, m. 143°; azide, m. 95°; sym-bis-3-indoxazenylurea, m. 244°; 3-aminoindoxazene, m. 110° (Ac derivative, m. 155-6°).

From this literature《Ring openings with benz-α,β-isoöxazoles. II》,we know some information about this compound(271-95-4)Name: 1,2-Benzisoxazole, but this is not all information, there are many literatures related to this compound(271-95-4).

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Recommanded Product: Quinolin-6-ylboronic acid. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Quinolin-6-ylboronic acid, is researched, Molecular C9H8BNO2, CAS is 376581-24-7, about Reaction scope and mechanistic insights of nickel-catalyzed migratory Suzuki-Miyaura cross-coupling. Author is Li, Yuqiang; Luo, Yixin; Peng, Long; Li, Yangyang; Zhao, Binzhi; Wang, Wang; Pang, Hailiang; Deng, Yi; Bai, Ruopeng; Lan, Yu; Yin, Guoyin.

In this work, a Ni-catalyzed migratory Suzuki-Miyaura cross-coupling featuring high benzylic or allylic selectivity has been developed. With this method, unactivated alkyl electrophiles and aryl or vinyl boronic acids can be efficiently transferred to diarylalkane or allylbenzene derivatives under mild conditions. Importantly, unactivated alkyl chlorides can also be successfully used as the coupling partners. To demonstrate the applicability of this method, showcase that this strategy can serve as a platform for the synthesis of terminal, partially deuterium-labeled mols. from readily accessible starting materials. Exptl. studies suggest that migratory cross-coupling products are generated from Ni(0/II) catalytic cycle. Theor. calculations indicate that the chain-walking occurs at a neutral nickel complex rather than a cationic one. In addition, the original-site cross-coupling products can be obtained by alternating the ligand, wherein the formation of the products has been rationalized by a radical chain process.

There is still a lot of research devoted to this compound(SMILES：OB(C1=CC=C2N=CC=CC2=C1)O)Recommanded Product: Quinolin-6-ylboronic acid, and with the development of science, more effects of this compound(376581-24-7) can be discovered.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Mosnacek, Jaroslav; Kundys, Anna; Andicsova, Anita published the article 《Reversible-deactivation radical polymerization of methyl methacrylate induced by photochemical reduction of various copper catalysts》. Keywords: methyl methacrylate copper catalyst atom transfer radical photo polymerization; UV visible light living controlled polymerization photochem reduction.They researched the compound: 2-Bromopropanenitrile( cas:19481-82-4 ).Synthetic Route of C3H4BrN. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:19481-82-4) here.

Photochem. mediated reversible-deactivation radical polymerization of Me methacrylate was successfully performed using 50-400 ppm of various copper compounds such as CuSO4.5H2O, copper acetate, copper triflate and copper acetylacetonate as catalysts. The copper catalysts were reduced in situ by irradiation at wavelengths of 366-546 nm, without using any addnl. reducing agent. Bromopropionitrile was used as an initiator. The effects of various solvents and the concentration and structure of ligands were investigated. Well-defined polymers were obtained when at least 100 or 200 ppm of any catalyst complexed with excess tris(2-pyridylmethyl)amine as a ligand was used in DMSO as a solvent.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Related Products of 376581-24-7. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Quinolin-6-ylboronic acid, is researched, Molecular C9H8BNO2, CAS is 376581-24-7, about Synthesis of proline analogs via Rh-catalyzed asymmetric conjugate addition. Author is Edelstein, Emma K.; Rankic, Danica A.; Dudley, Caroline C.; McMinn, Spencer E.; Adpressa, Donovon A..

An enantio- and diastereoselective Rh-catalyzed conjugate addition reaction for the synthesis of proline analogs is reported. A high-throughput experimentation campaign was used to identify an efficient chiral catalyst which was able to afford the desired products in high yield and with high levels of diastereo- and enantioselectivity. This method was used to afford a range of 3-substituted proline derivatives from readily available dehydroproline electrophiles and boronic acid nucleophiles.

There is still a lot of research devoted to this compound(SMILES：OB(C1=CC=C2N=CC=CC2=C1)O)Related Products of 376581-24-7, and with the development of science, more effects of this compound(376581-24-7) can be discovered.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Journal of Organic Chemistry called On the Magnitude and Specificity of Medium Effects in Enzyme-like Catalysts for Proton Transfer, Author is Hollfelder, Florian; Kirby, Anthony J.; Tawfik, Dan S., which mentions a compound: 271-95-4, SMILESS is C12=CC=CC=C1ON=C2, Molecular C7H5NO, Computed Properties of C7H5NO.

Medium effects are normally studied by comparing the rates of reactions in different solvents. However, medium effects at the active site of enzymes differ dramatically from bulk solvents, both in their diversity (the presence of more than one type of “”solvent””) and in their spatial arrangement. We describe medium effects in a simple catalytic system, obtained by systematic alkylation of a polymeric scaffold bearing amine groups to give synzymes that catalyze the Kemp elimination of benzisoxazoles with remarkable efficiency. Our anal. indicates that catalysis by these synzymes is driven primarily by specific, localized enzyme-like medium effects, and these effects seem to differ dramatically from the nonspecific medium effects (i.e., desolvation activation) exhibited by solvents. Ligand-binding studies indicate that the synzyme active sites provide localized microenvironments affording a combination of hydrophobic and apolar regions on one hand and dipolar, protic, and pos. charged on the other. Such localized microenivronments are not available in bulk solvents. A Bronsted (leaving group) anal. indicates that, in comparison to solvent catalysis, the efficiency of synzyme catalysis shows little sensitivity to leaving group pKa. We show that enzyme-like medium effects alone, in the absence of efficient positioning of the catalytic amine base relative to the substrate, can give rise to rate accelerations as high as 105, for both activated and nonactivated substrates. Supported by the accidental identification of active sites on the surfaces of noncatalytic proteins and the promiscuous activities found in many enzymes, our findings suggest that the interfaces of protein surfaces and their hydrophobic cores provide a microenvironment that is intrinsically active and may serve as a basis for further evolutionary improvements to give proficient and selective enzymes.

From this literature《On the Magnitude and Specificity of Medium Effects in Enzyme-like Catalysts for Proton Transfer》,we know some information about this compound(271-95-4)Computed Properties of C7H5NO, but this is not all information, there are many literatures related to this compound(271-95-4).

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Ferris, J. P.; Antonucci, F. R. published the article 《Synthesis of heterocycles by photochemical cyclization of o-substituted benzene derivatives》. Keywords: ring closure benzenes photochem; indazoles irradiation anthranilonitriles; carbazole irradiation anthranilonitriles; benzimidazole irradiation anthranilonitrile; benzoxazole irradiation cyanophenol; benzofuran irradiation ethynylphenol.They researched the compound: 1,2-Benzisoxazole( cas:271-95-4 ).Name: 1,2-Benzisoxazole. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:271-95-4) here.

Irradiation of anthranilonitrile gave indazole, which on further irradiation gave benzimidazole. Irradiation of N-methyl-and N-phenylanthraniloni-trile gave 17% 1-methylindazole and 87% carbazole, resp. Irradiation of 2-cyanophenol gave 60% benzoxazole and irradiation of o-ethynylphenol gave 60% benzofuran and 20% o-AcC6H4OH.

From this literature《Synthesis of heterocycles by photochemical cyclization of o-substituted benzene derivatives》,we know some information about this compound(271-95-4)Name: 1,2-Benzisoxazole, but this is not all information, there are many literatures related to this compound(271-95-4).

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 376581-24-7, is researched, Molecular C9H8BNO2, about A Highly Efficient Catalyst for the Suzuki-Miyaura Cross-Coupling Reaction of 5-(5-chloropyridin-3-yl)-3-methyl-1,3,4-oxadiazol-2(3H)-one, the main research direction is aryl heteroaryl pyridyl oxadiazolone preparation microwave irradiation; chloropyridinyl methyl oxadiazolone boronic acid Suzuki Miyaura cross coupling.Category: ruthenium-catalysts.

A highly efficient protocol for the synthesis of diverse aryl(heteroaryl) substituted pyridyl oxadiazol-2(3H)-one analogs using Suzuki-Miyaura cross-coupling strategy under microwave irradiation conditions is developed. The method is found to be compatible with a wide range of aryl(heteroaryl) boronic acids.

There is still a lot of research devoted to this compound(SMILES：OB(C1=CC=C2N=CC=CC2=C1)O)Category: ruthenium-catalysts, and with the development of science, more effects of this compound(376581-24-7) can be discovered.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 376581-24-7, is researched, Molecular C9H8BNO2, about Catalyst-free arylation of sulfonamides via visible light-mediated deamination, the main research direction is diaryl sulfone preparation photochem; sulfonamide aryl boronic acid arylation deamination visible light.Category: ruthenium-catalysts.

A novel arylation of sulfonamides RSO2N(R1)C(O)R2 (R = 4-methylphenyl, naphthalen-2-yl, 2,3-dihydro-1-benzofuran-6-yl, etc.; R1 = Ph, Me, Bn, etc.; R2 = Ph, Me, Bn, n-pentyl, 4-cyanophenyl) with boronic acids R3B(OH)2 [R3 = 4-(methoxycarbonyl)phenyl, 4-methylnaphthalen-1-yl, 1-benzofuran-2-yl, etc.] to afford numerous diaryl sulfones RS(O)2R3 via a visible light-mediated N-S bond cleavage, rather than the typical transition-metal-catalyzed C(O)-N bond activation, is described. This methodol., which represents the first catalyst-free protocol for the sulfonylation of boronic acids, is characterized by its simple reaction conditions, good functional group tolerance and high efficiency. Several successful examples for the late-stage functionalization of diverse sulfonamides indicate the high potential utility of this method in pharmaceutical science and organic synthesis.

There is still a lot of research devoted to this compound(SMILES：OB(C1=CC=C2N=CC=CC2=C1)O)Category: ruthenium-catalysts, and with the development of science, more effects of this compound(376581-24-7) can be discovered.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI