10/9/2021 News Brief introduction of Tetrapropylammonium perruthenate

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The present invention provides a fused ring compound containing furan or a pharmaceutically acceptable salt thereof, a method for preparing same, a pharmaceutical composition comprising same, and a use thereof. The fused ring compound containing furan or a pharmaceutically acceptable salt thereof inhibits the activity of phosphatidylinositol 3-kinase (PI3K) and can therefore be used in a pharmaceutical composition for treating and preventing respiratory diseases, inflammatory diseases, proliferative diseases, cardiovascular diseases, or central nervous system diseases which occur due to the over-activation of PI3K.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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In the absence of an oxidant, tetrapropylammonium perruthenate (TPAP) is reduced by 2-undecanol to a low-valent ruthenium species that efficiently catalyzes the isomerization of a wide range of allylic alcohols into the corresponding saturated carbonyl derivatives [Eq.(1)]. R1, R2, R3, R4 = alkyl, aryl, H.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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Compounds of the formula: wherein R1, Y, W, A and R2 are as defined above are inhibitors of rotamase enzymes in particular FKBP-12 and FKBP-52. The compounds therefore moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.114615-82-6, Name is Tetrapropylammonium perruthenate, molecular formula is C12H28NO4Ru. In a Patent,once mentioned of 114615-82-6, Recommanded Product: Tetrapropylammonium perruthenate

Disclosed is a synthesis method of chiral tetrahydroquinoline derivatives. According to the present invention, chiral tetrahydroquinoline derivatives having high optical purity can be efficiently synthesized from cinnamyl alcohol derivatives using tetrapropylammonium perruthenate as a catalyst and a chiral catalyst in the presence of oxygen (O_2).COPYRIGHT KIPO 2016

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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The first total synthesis of violaceoid A, a cytotoxic agent, and the asymmetric total synthesis of (-)- and (+)-violaceoid B are reported. The precursor was accessed by desymmetrization of a substituted quinol moiety, and the racemic secondary alcohol was kinetically resolved using a chiral nucleophilic catalyst. The asymmetric synthesis of (-)- and (+)-violaceoid B elucidated the absolute configuration of the naturally occurring violaceoid B. Synthetic violaceoid A inhibited the growth of human breast cancer cell lines MCF-7 and Hs 578T at concentrations of less than 100 muM, while (S)- and (R)-violaceoid B were inactive.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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Provided herein are formulations, methods and substituted tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Sep 2021 News Simple exploration of Tetrapropylammonium perruthenate

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 114615-82-6, Name is Tetrapropylammonium perruthenate, molecular formula is C12H28NO4Ru. In a Patent,once mentioned of 114615-82-6, Quality Control of: Tetrapropylammonium perruthenate

Compounds of formula (I): wherein R1, R2 and R3 are defined in the specification. The compounds are useful for treating or reducing the risk of reversible obstructive airways disease

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Sep 2021 News Brief introduction of Tetrapropylammonium perruthenate

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114615-82-6, Name is Tetrapropylammonium perruthenate, molecular formula is C12H28NO4Ru, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 114615-82-6, SDS of cas: 114615-82-6

This invention describes C1-C6-epothilone fragments and an efficient process for the production of C1-C6-fragments of epothilones and derivatives thereof.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

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The present invention relates to phenoxy-azetidine derivatives of Formula I, processes for preparing them, pharmaceutical compositions containing them, and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.

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Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI