Tag: M.W:400-500

Application of 37366-09-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 37366-09-9, Name is Dichloro(benzene)ruthenium(II) dimer, molecular formula is C12H12Cl4Ru2. In a Article，once mentioned of 37366-09-9

It is now well established that ruthenium complexes are attractive alternatives to platinum-based anticancer agents. Most of the ruthenium compounds currently under investigation contain a single metal center. The synthesis of multinuclear analogues may provide access to novel complexes with enhanced biological activity. In this work, we have synthesized a set of three trinuclear complexes containing organometallic ruthenium fragments?(arene)RuCl?coordinated to a 2,4,6-tris(di2-pyridylamino)-1,3,5-triazine core [(Arene=benzene (2), p-cymene (1), or hexamethylbenzene (3)]. The interaction of the complexes with DNA was extensively studied using a variety of biophysical probes as well as by molecular docking. The complexes bind strongly to DNA with apparent binding constants ranging from 2.20 to 4.79 ×104 M?1. The binding constants from electronic absorption titrations were an order of magnitude greater. The mode of binding to the nucleic acid was not definitively determined, but the evidence pointed to some kind of non-specific electrostatic interaction. None of the complexes displayed any significant antimicrobial activity against the organisms that were studied and exhibited anticancer activity only at high (>100 muM) concentration.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 37366-09-9 is helpful to your research., Application of 37366-09-9

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 37366-09-9, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.37366-09-9, Name is Dichloro(benzene)ruthenium(II) dimer, molecular formula is C12H12Cl4Ru2. In a patent, introducing its new discovery.

Ionic liquids comprised of cationic arene-ruthenium chelate complexes and the bis(trifluoromethanesulfonyl)amide anion (=Tf2N), [(arene)RuCl(L)](Tf2N), where L = MeS(CH2)nSR (R = Me, Bu; n = 1-3), Me2N(CH2)2NMe 2 and arene = p-cymene, C6H6, have been prepared, and their thermal properties, structures, and reactivities have been investigated. These liquids undergo direct ligand exchange reactions in line with their thermal stabilities. Thermogravimetric analysis revealed that the thermal stabilities of the complexes are higher as the bridging group of the chelate ligand becomes longer. The complexes with MeSCH2SMe transform thermally into dinuclear complexes. The coordination structures were determined crystallographically.

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Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

37366-09-9, Name is Dichloro(benzene)ruthenium(II) dimer, molecular formula is C12H12Cl4Ru2, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 37366-09-9, Recommanded Product: 37366-09-9

The DNA binding of cationic complexes of the type [(eta6-arene)Ru(Aa)(dppz)] (CF3SO3)n (arene = C6H6, Me3C6H3, C6Me6; dppz = dipyrido[3,2-a:2?,3?-c]phenazine; n = 1, Aa = AcH-1cysOH 4-6; n = 2, Aa = AcmetOH 7-9; n = 3, Aa = H2metOMe 10-12) containing S-coordinated amino acids (HcysOH = L-cysteine, HmetOH = L-methionine) has been studied by UV-vis titration and 2D-NOESY. Stable intercalative binding is indicated for these complexes by their steady decrease in absorbance at maxima between 350 and 390 nm on titration with CT DNA and the bathochromic shifts of these absorption maxima. Taking 4-12 and the analogous (eta6-C6Me6)RuII complexes of the tripeptides HglyglycysOH (n = 1, 13) and HglyglymetOH (n = 2, 15; HglyOH = glycine) into account, typical DNA binding constant (Kb) ranges can be established for (eta6-arene)RuII complexes: 5.3 × 104-1.6 × 105 M-1 for monocations, 6.3 × 105 9.9 × 105 M-1 for dications and 1.6 × 106-5.5 × 106 M-1 for trications. These Kb values clearly reflect a strengthening of electrostatic interactions with the negatively charged phosphodiester backbone of DNA as the total cation charge increases. A consistent trend to higher Kb values is also apparent for the coligand series C6H6 < Me3C6H3 < C6Me6 with the relative increase being, in general, more pronounced for C6H6/Me3C6H3 pairs. The strong electronic influence of the coligand on dppz intercalation is also reflected by marked increases DeltaTm of 18.2-18.5 C in the CT DNA thermal denaturation temperature for di- and tri-cationic (eta6-C6Me6)RuII complexes. Upfield 1H NMR chemical shifts and characteristic NOE cross peaks for the dppz protons of the 1 : 1 complex formed between 9 and d(GTCGAC)2 are consistent with a side-on intercalation adjacent to T2 from the major groove. Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 37366-09-9. In my other articles, you can also check out more blogs about 37366-09-9

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15746-57-3, Name is Cis-Dichlorobis(2,2′-bipyridine)ruthenium(II), molecular formula is C20H16Cl2N4Ru, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 15746-57-3, Formula: C20H16Cl2N4Ru

Targeted delivery of clinically approved anticancer drug to tumor sites is an effective way to achieve enhanced drug efficacy as well as reduced side effects and toxicity. Here bicalutamide is caged by the Ru(II) center through the nitrile group, and three photoactive Ru(II) complexes were designed and synthesized. Docking study showed that the ruthenium(II) fragments can effectively block the binding of complexes 1?3 with AR (androgen receptor) owing to the large steric structures, thus bicalutamide in complexes 1?3 could not interact with AR-LBD (ligand binding domain). Once irradiation with blue light (465 nm), complexes 1?3 can release bicalutamide and anticancer Ru(II) fragments, which possesses dual-action of AR binding and DNA interaction simultaneously. In vitro cytotoxicity study on these complexes further confirmed that complexes 1?3 exhibited considerable cytotoxicity upon irradiation with blue light. Significantly, complex 3 could be activated at 660 nm, which greatly increases the scope of complex 3 to treat deeper within tissue. Theoretical calculations showed that the lowest singlet excitation energy of complex 3 is lower than those of complexes 1?2, which explains the experimental results well. Moreover, the 3MC (metal centered) states of these complexes are more stable than their 3MLCT (metal to ligand charge transfer) states, indicating that the photoactive processes of these complexes are likely to result in ligand dissociation.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Formula: C20H16Cl2N4Ru. In my other articles, you can also check out more blogs about 15746-57-3

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 15746-57-3, Name is Cis-Dichlorobis(2,2′-bipyridine)ruthenium(II), molecular formula is C20H16Cl2N4Ru. In a Article，once mentioned of 15746-57-3, Formula: C20H16Cl2N4Ru

A series of Ru(II)/arene complexes containing N-alkylated derivatives of TsDPEN were prepared and tested in the asymmetric transfer hydrogenation (ATH) of ketones. The results demonstrated that a wide variety of functionality were tolerated on the basic amine of the TsDPEN ligand, without significantly disrupting the ability of the catalyst to catalyse hydrogen transfer reactions.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Formula: C20H16Cl2N4Ru, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 15746-57-3, in my other articles.

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15746-57-3, Name is Cis-Dichlorobis(2,2′-bipyridine)ruthenium(II), molecular formula is C20H16Cl2N4Ru, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 15746-57-3, Quality Control of: Cis-Dichlorobis(2,2′-bipyridine)ruthenium(II)

The synthesis and characterization of two new RuII complexes, a mononuclear complex [RuII(MeMPTP)(bpp)Cl]PF6 (1) and a dinuclear complex [RuII(MeMPTP)(bpp)RuII(bpy)2Cl](PF6)3 (2), [where MeMPTP = 4?-(4-methylmercaptophenyl)-2,2?:6?2??-terpyridine, bpp = 2,3-bis(2-pyridyl)pyrazine, bpy = 2,2?-bipyridine] is reported. Single-crystal X-ray structural determination of the compounds unambiguously confirms the formation of the complexes 1 and 2. Catalytic investigations of the complexes for the chemical oxidation of water in the presence of Ce4+ as a sacrificial oxidant reveals a higher rate of O2 evolution by the dinuclear complex 2 over the physical mixture of complex 1 and a redox mediator, [Ru(bpy)3]2+ (med), followed by the mononuclear complex 1. The enhancement in the catalytic rate of O2 evolution by 2 is ascribed to being due to the intramolecular redox process, which facilitates the facile formation of a high-valent ruthenium?oxo species that is required for water oxidation through a cooperative effect. The present study highlights the importance of the intramolecular redox process over the intermolecular redox process.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: Cis-Dichlorobis(2,2′-bipyridine)ruthenium(II). In my other articles, you can also check out more blogs about 15746-57-3

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.15746-57-3, Name is Cis-Dichlorobis(2,2′-bipyridine)ruthenium(II), molecular formula is C20H16Cl2N4Ru. In a Article，once mentioned of 15746-57-3, Formula: C20H16Cl2N4Ru

A series of mononuclear Ru trisbypiridine complexes connected to an anthraquinone unit by a flexible alkyl chain of varying lengths and a bolaamphiphilic dinuclear ruthenium complex bearing an anthraquinone unit in the middle of alkyl chain spacers were synthesized. Their conformational preference in CH3CN and in dihexadecyl phosphate vesicles was probed by utilizing the intramolecular electron-transfer quenching of the metal-to-ligand charge-transfer excited state of the Ru center by the appended quinone moiety. The length of the alkyl chain spacer had little effect on the quenching efficiency in either medium. A marked difference in the quenching behavior was observed only in the case of the dinuclear Ru complex in vesicles. These results indicate that the bolaamphiphilic structure is necessary and effective for the set of immobilized molecules to take a stretched conformation spanning a bilayer membrane.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Formula: C20H16Cl2N4Ru, you can also check out more blogs about15746-57-3

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 37366-09-9, Name is Dichloro(benzene)ruthenium(II) dimer, molecular formula is C12H12Cl4Ru2. In a Article，once mentioned of 37366-09-9, HPLC of Formula: C12H12Cl4Ru2

A general electropolymerization/electro-oligomerization strategy is described for preparing spatially controlled, multicomponent films and surface assemblies having both light harvesting chromophores and water oxidation catalysts on metal oxide electrodes for applications in dye-sensitized photoelectrosynthesis cells (DSPECs). The chromophore/catalyst ratio is controlled by the number of reductive electrochemical cycles. Catalytic rate constants for water oxidation by the polymer films are similar to those for the phosphonated molecular catalyst on metal oxide electrodes, indicating that the physical properties of the catalysts are not significantly altered in the polymer films. Controlled potential electrolysis shows sustained water oxidation over multiple hours with no decrease in the catalytic current.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.HPLC of Formula: C12H12Cl4Ru2. In my other articles, you can also check out more blogs about 37366-09-9

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.37366-09-9, Name is Dichloro(benzene)ruthenium(II) dimer, molecular formula is C12H12Cl4Ru2. In a Article，once mentioned of 37366-09-9, Application In Synthesis of Dichloro(benzene)ruthenium(II) dimer

Four metal complexes, IL-OPPh2-Ru-p-cymene (3), IL-OPPh2-Ru-benzene (4), IL-OPPh2-Ir-Cp* (5), IL-OPPh2-Rh-COD (6), have been evaluated for in vitro antioxidant activity such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and reducing power activity. Maximum scavenging activity (71.43%) was obtained with IL-OPPh2-Ru-p-cymene, whereas IL-OPPh2-Rh-COD showed the highest reducing power ability. The complexes were also studied for their antimicrobial activity against three Gram-positive and three Gram-negative bacteria. In addition, DNA binding of the complexes was evaluated using calf thymus DNA. Both Ru(II) complexes exhibited good DNA-binding activity while the other complexes did not have any activity. Furthermore, ab initio quantum calculations of four complexes were also carried out using density functional theory to better understand their chemical behaviors.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of Dichloro(benzene)ruthenium(II) dimer, you can also check out more blogs about37366-09-9

Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 37366-09-9, An article , which mentions 37366-09-9, molecular formula is C12H12Cl4Ru2. The compound – Dichloro(benzene)ruthenium(II) dimer played an important role in people’s production and life.

A novel approach to design bimetallic anticancer drug candidates with the capability to combat both drug resistance and tumor metastasis is reported. These water-soluble bifunctional Pt(iv)-Ru(ii) heterodinuclear complexes with a unique mode of action display up to 2-orders of magnitude enhanced cytotoxicity in cisplatin-resistant cells and significantly impede cancer cell migration.

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Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI