Tag: M.W:700-800

32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II), molecular formula is C41H35ClP2Ru, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 32993-05-8, category: ruthenium-catalysts

Preparation of diazoalkane complexes of ruthenium and their cyclization reactions with alkenes and alkynes

The diazoalkane complexes [Ru(eta5-C5H 5)(N2CAr1Ar2)(PPh3)(L)]BPh4 (1-5: Ar1 = Ar2 = Ph (a), Ar1 = Ph and Ar2 = p-tolyl (b), Ar1Ar2 = C 12H8 (c), Ar1 = Ph and Ar2 = PhCO (d); L = PPh3 (1), P(OMe)3 (2), P(OEt)3 (3), PPh(OEt)2 (4), ButNC (5)) were prepared by allowing the chloro compounds RuCl(eta5-C5H5)(PPh3)(L) to react with the diazoalkanes Ar1Ar2CN2 in ethanol. Treatment of complexes 1-5 with ethylene (CH2=CH2) under mild conditions (1 atm, room temperature) led not only to the eta2-ethylene complexes [Ru(eta5-C5H5)(eta2-CH 2=CH2)(PPh3)(L)]BPh4 (10-14) but also to dipolar (3 + 2) cycloaddition, affording the 4,5-dihydro-3H-pyrazole derivatives [Ru(eta5-C5H5){eta1- N=NC(Ar1Ar2)CH2CH2}(PPh3)(L)]BPh4 (6-9). Acrylonitrile (CH2=C(H)CN) reacted with diazoalkane complexes 2 and 3 to give the 1H-pyrazoline derivatives [Ru(eta5-C 5H5){eta1-N=C(CN)CH2C(Ar1Ar2)NH} (PPh3)(L)]BPh4 (19, 20). However, reactions with propylene (CH2=C(H)CH3), maleic anhydride (ma, CH=CHCO(O)CO) and dimethyl maleate (dmm, CH3OCOCH=CHOCOCH3) led to the eta2-alkene complexes [Ru(eta5-C5H 5)(eta2-R1CH=CHR2)(PPh3)(L)]BPh4 (17-22). Treatment of the diazoalkane complexes 1 and 2 with acetylene CH?CH under mild conditions (1 atm, room temperature) led to dipolar cycloaddition, affording the 3H-pyrazole complexes [Ru(eta5-C 5H5){eta1-N=NC(Ar1Ar2)CH=CH}(PPh 3){P(OMe)3}]BPh4 (24), whereas reactions with the terminal alkynes PhC?CH and ButC?CH gave the vinylidene derivatives [Ru(eta5-C5H5){=C=C(H) R}(PPh3){P(OMe)3}]BPh4 (25, 26). The alkyl propiolates HC?CCOOR1 (R1 = Me, Et) also reacted with complexes 2 to give the 3H-pyrazole complexes [Ru(eta5-C5H 5){eta1-N=NC(Ar1Ar2)C(COOR1)=CH}(PPh3){P(OMe) 3}]BPh4 (27, 28). The complexes were characterized by spectroscopy and by X-ray crystal structure determinations of [Ru(eta5-C5H5){eta1-N=C(CN) CH2C(Ph)(p-tolyl)NH}(PPh3){P(OMe)3}]BPh 4 (19b), [Ru(eta5-C5H5) {eta2-CH=CHCO(O)CO}(PPh3){P(OMe)3}]BPh 4 (21), and [Ru(eta5-C5H5) {eta1-N=NC(C12H8)CH=CH}(PPh 3){P(OMe)3}]BPh4 (24c).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.category: ruthenium-catalysts. In my other articles, you can also check out more blogs about 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Related Products of 32993-05-8. Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II). In a document type is Article, introducing its new discovery.

Ruthenium hydride complexes of chiral and achiral diphosphazane ligands and asymmetric transfer hydrogenation reactions

The half-sandwhich ruthenium chloro complexes bearing chelated diphosphazane ligands, [(eta5-Cp)RuCl{kappa2-P,P-(RO)2PN(M e)P(OR)2}] [R = C6H3Me2-2,6] (1) and [(eta5-Cp*)RuCl{kappa2- P,P-X2PN(R)PYY?}] [R = Me, X = Y = Y? = OC6H5 (2); R = CHMe2, X2 = C20H12O2, Y = Y? = OC6H5 (3) or OC6H4tBu-4 (4)] have been prepared by the reaction of CpRu(PPh3)2Cl with (RO)2PN(Me)P(OR)2 [R = C6H3Me2-2,6 (L1)] or by the reaction of [Cp*RuCl2]n with X2PN(R)PYY? in the presence of zinc dust. Among the four diastereomers (two enantiomeric pairs) possible for the “chiral at metal” complexes 3 and 4, only two diastereomers (one enantiomeric pair) are formed in these reactions. The complexes 1, 2, 4 and [(eta5-Cp)RuCl{kappa2-P,P-Ph2PN((S) -*CHMePh)PPhY}] [Y = Ph (5) or N2C3HMe2-3,5 (SCSPRRu)-(6)] react with NaOMe to give the corresponding hydride complexes [(eta5-Cp)RuH{kappa2-P,P-(RO)2PN(Me )P(OR)2}] (7), [(eta5-Cp*)RuH{kappa2-P, P?-X2PN(R)PY2}] [R = Me, X = Y = OC6H5 (8); R = CHMe2, X2 = C20H12O2, Y = OC6H4tBu-4 (9)] and [(eta5-Cp)RuH{kappa2-P,P-Ph2PN((S)- *CHMePh)PPhY}][Y = Ph (10) or N2C3HMe2-3,5 (SCSPRRu)-(11a) and (SCSPSRu)-(11b)]. Only one enantiomeric pair of the hydride 9 is obtained from the chloro precursor 4 that bears sterically bulky substituents at the phosphorus centers. On the other hand, the optically pure trichiral complex 6 that bears sterically less bulky substituents at the phosphorus gives a mixture of two diastereomers (11a and 11b). Protonation of complex 7 using different acids (HX) gives a mixture of [(eta5-Cp)Ru(eta2-H2){kappa 2-P,P-(RO)2PN(Me)P(OR)2}]X (12a) and [(eta5-Cp)Ru(H)2{kappa2-P,P-(RO) 2PN(Me)P(OR)2}]X (12b) of which 12a is the major product independent of the acid used; the dihydrogen nature of 12a is established by T1 measurements and also by synthesizing the deuteride analogue 7-D followed by protonation to obtain the D-H isotopomer. Preliminary investigations on asymmetric transfer hydrogenation of 2-acetonaphthone in the presence of a series of chiral diphosphazane ligands show that diphosphazanes in which the phosphorus centers are strong pi-acceptor in character and bear sterically bulky substituents impart moderate levels of enantioselectivity. Attempts to identify the hydride intermediate involved in the asymmetric transfer hydrogenation by a model reaction suggests that a complex of the type, [Ru(H)(Cl){kappa2-P,P-X2PN(R)PY2}(sol vent)2] could be the active species in this transformation.

If you are interested in 32993-05-8, you can contact me at any time and look forward to more communication.Related Products of 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II), molecular formula is C41H35ClP2Ru. In a Article£¬once mentioned of 32993-05-8, Safety of Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II)

Synthesis and biological assessment of a ruthenium(II) cyclopentadienyl complex in breast cancer cells and on the development of zebrafish embryos

Ruthenium-based complexes currently attract great attention as they hold promise to replace platinum-based drugs as a first line cancer treatment. Whereas ruthenium arene complexes are some of the most studied species for their potential anticancer properties, other types of ruthenium complexes have been overlooked for this purpose. Here, we report the synthesis and characterization of Ru(II) cyclopentadienyl (Cp), Ru(II) cyclooctadienyl (COD) and Ru(III) complexes bearing anastrozole or letrozole ligands, third-generation aromatase inhibitors currently used for the treatment of estrogen receptor positive (ER +) breast cancer. Among these complexes, Ru(II)Cp 2 was the only one that displayed a high stability in DMSO and in cell culture media and consequently, the only complex for which the in vitro and in vivo biological activities were investigated. Unlike anastrozole alone, complex 2 was considerably cytotoxic in vitro (IC50 values < 1 muM) in human ER + breast cancer (T47D and MCF7), triple negative breast cancer (TNBC) (MBA-MB-231), and in adrenocortical carcinoma (H295R) cells. Theoretical (docking simulation) and experimental (aromatase catalytic activity) studies suggested that an interaction between 2 and the aromatase enzyme was not likely to occur and that the bulkiness of the PPh3 ligands could be an important factor preventing the complex to reach the active site of the enzyme. Exposure of zebrafish embryos to complex 2 at concentrations around its in vitro cytotoxicity IC50 value (0.1?1 muM) did not lead to noticeable signs of toxicity over 96 h, making it a suitable candidate for further in vivo investigations. This study confirms the potential of Ru(II)Cp complexes for breasts cancer therapy, more specifically against TNBCs that are usually not responsive to currently used chemotherapeutic agents. Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Safety of Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II). In my other articles, you can also check out more blogs about 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 32993-05-8. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II)

Access to novel fluorovinylidene ligands via exploitation of outer-sphere electrophilic fluorination: New insights into C-F bond formation and activation

Metal vinylidene complexes are widely encountered, or postulated, as intermediates in a range of important metal-mediated transformations of alkynes. However, fluorovinylidene complexes have rarely been described and their reactivity is largely unexplored. By making use of the novel outer-sphere electrophilic fluorination (OSEF) strategy we have developed a rapid, robust and convenient method for the preparation of fluorovinylidene and trifluoromethylvinylidene ruthenium complexes from non-fluorinated alkynes. Spectroscopic investigations (NMR and UV/Vis), coupled with TD-DFT studies, show that fluorine incorporation results in significant changes to the electronic structure of the vinylidene ligand. The reactivity of fluorovinylidene complexes shows many similarities to non-fluorinated analogues, but also some interesting differences, including a propensity to undergo unexpected C-F bond cleavage reactions. Heating fluorovinylidene complex [Ru(eta5-C5H5)(PPh3)2(CC{F}R)][BF4] led to C-H activation of a PPh3 ligand to form an orthometallated fluorovinylphosphonium ligand. Reaction with pyridine led to nucleophilic attack at the metal-bound carbon atom of the vinylidene to form a vinyl pyridinium species, which undergoes both C-H and C-F activation to give a novel pyridylidene complex. Addition of water, in the presence of chloride, leads to anti-Markovnikov hydration of a fluorovinylidene complex to form an alpha-fluoroaldehyde, which slowly rearranges to its acyl fluoride isomer. Therefore, fluorovinylidenes ligands may be viewed as synthetic equivalents of 1-fluoroalkynes providing access to reactivity not possible by other routes.

If you are hungry for even more, make sure to check my other article about 32993-05-8. Application of 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 14564-35-3, Name is Dichlorodicarbonylbis(triphenylphosphine)ruthenium(II), molecular formula is C38H34Cl2O2P2Ru. In a Article£¬once mentioned of 14564-35-3, Recommanded Product: Dichlorodicarbonylbis(triphenylphosphine)ruthenium(II)

HOMOGENEOUS HYDROGENATION OF ALDEHYDES TO ALCOHOLS WITH RUTHENIUM COMPLEX CATALYSTS

A number of ruthenium complexes catalyse the reduction of aldehydes to their corresponding alcohols in toluene solution under mild reaction conditions.The most convenient catalyst precursor is hydridochlorocarbonyltris(triphenylphosphine)ruthenium(II).Turnover numbers up to 32 000 have been achieved with this catalyst.The rate of hydrogenation is first order with respect to the substrate concentration, the catalyst concentration and the hydrogen pressure, and is also affected by acid and basic additives.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: Dichlorodicarbonylbis(triphenylphosphine)ruthenium(II). In my other articles, you can also check out more blogs about 14564-35-3

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II), molecular formula is C41H35ClP2Ru, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 32993-05-8, Recommanded Product: 32993-05-8

Preparation of diazoalkane complexes of ruthenium and their cyclization reactions with alkenes and alkynes

The diazoalkane complexes [Ru(eta5-C5H 5)(N2CAr1Ar2)(PPh3)(L)]BPh4 (1-5: Ar1 = Ar2 = Ph (a), Ar1 = Ph and Ar2 = p-tolyl (b), Ar1Ar2 = C 12H8 (c), Ar1 = Ph and Ar2 = PhCO (d); L = PPh3 (1), P(OMe)3 (2), P(OEt)3 (3), PPh(OEt)2 (4), ButNC (5)) were prepared by allowing the chloro compounds RuCl(eta5-C5H5)(PPh3)(L) to react with the diazoalkanes Ar1Ar2CN2 in ethanol. Treatment of complexes 1-5 with ethylene (CH2=CH2) under mild conditions (1 atm, room temperature) led not only to the eta2-ethylene complexes [Ru(eta5-C5H5)(eta2-CH 2=CH2)(PPh3)(L)]BPh4 (10-14) but also to dipolar (3 + 2) cycloaddition, affording the 4,5-dihydro-3H-pyrazole derivatives [Ru(eta5-C5H5){eta1- N=NC(Ar1Ar2)CH2CH2}(PPh3)(L)]BPh4 (6-9). Acrylonitrile (CH2=C(H)CN) reacted with diazoalkane complexes 2 and 3 to give the 1H-pyrazoline derivatives [Ru(eta5-C 5H5){eta1-N=C(CN)CH2C(Ar1Ar2)NH} (PPh3)(L)]BPh4 (19, 20). However, reactions with propylene (CH2=C(H)CH3), maleic anhydride (ma, CH=CHCO(O)CO) and dimethyl maleate (dmm, CH3OCOCH=CHOCOCH3) led to the eta2-alkene complexes [Ru(eta5-C5H 5)(eta2-R1CH=CHR2)(PPh3)(L)]BPh4 (17-22). Treatment of the diazoalkane complexes 1 and 2 with acetylene CH?CH under mild conditions (1 atm, room temperature) led to dipolar cycloaddition, affording the 3H-pyrazole complexes [Ru(eta5-C 5H5){eta1-N=NC(Ar1Ar2)CH=CH}(PPh 3){P(OMe)3}]BPh4 (24), whereas reactions with the terminal alkynes PhC?CH and ButC?CH gave the vinylidene derivatives [Ru(eta5-C5H5){=C=C(H) R}(PPh3){P(OMe)3}]BPh4 (25, 26). The alkyl propiolates HC?CCOOR1 (R1 = Me, Et) also reacted with complexes 2 to give the 3H-pyrazole complexes [Ru(eta5-C5H 5){eta1-N=NC(Ar1Ar2)C(COOR1)=CH}(PPh3){P(OMe) 3}]BPh4 (27, 28). The complexes were characterized by spectroscopy and by X-ray crystal structure determinations of [Ru(eta5-C5H5){eta1-N=C(CN) CH2C(Ph)(p-tolyl)NH}(PPh3){P(OMe)3}]BPh 4 (19b), [Ru(eta5-C5H5) {eta2-CH=CHCO(O)CO}(PPh3){P(OMe)3}]BPh 4 (21), and [Ru(eta5-C5H5) {eta1-N=NC(C12H8)CH=CH}(PPh 3){P(OMe)3}]BPh4 (24c).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 32993-05-8. In my other articles, you can also check out more blogs about 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 32993-05-8. Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II). In a document type is Article, introducing its new discovery.

Ruthenium hydride complexes of chiral and achiral diphosphazane ligands and asymmetric transfer hydrogenation reactions

The half-sandwhich ruthenium chloro complexes bearing chelated diphosphazane ligands, [(eta5-Cp)RuCl{kappa2-P,P-(RO)2PN(M e)P(OR)2}] [R = C6H3Me2-2,6] (1) and [(eta5-Cp*)RuCl{kappa2- P,P-X2PN(R)PYY?}] [R = Me, X = Y = Y? = OC6H5 (2); R = CHMe2, X2 = C20H12O2, Y = Y? = OC6H5 (3) or OC6H4tBu-4 (4)] have been prepared by the reaction of CpRu(PPh3)2Cl with (RO)2PN(Me)P(OR)2 [R = C6H3Me2-2,6 (L1)] or by the reaction of [Cp*RuCl2]n with X2PN(R)PYY? in the presence of zinc dust. Among the four diastereomers (two enantiomeric pairs) possible for the “chiral at metal” complexes 3 and 4, only two diastereomers (one enantiomeric pair) are formed in these reactions. The complexes 1, 2, 4 and [(eta5-Cp)RuCl{kappa2-P,P-Ph2PN((S) -*CHMePh)PPhY}] [Y = Ph (5) or N2C3HMe2-3,5 (SCSPRRu)-(6)] react with NaOMe to give the corresponding hydride complexes [(eta5-Cp)RuH{kappa2-P,P-(RO)2PN(Me )P(OR)2}] (7), [(eta5-Cp*)RuH{kappa2-P, P?-X2PN(R)PY2}] [R = Me, X = Y = OC6H5 (8); R = CHMe2, X2 = C20H12O2, Y = OC6H4tBu-4 (9)] and [(eta5-Cp)RuH{kappa2-P,P-Ph2PN((S)- *CHMePh)PPhY}][Y = Ph (10) or N2C3HMe2-3,5 (SCSPRRu)-(11a) and (SCSPSRu)-(11b)]. Only one enantiomeric pair of the hydride 9 is obtained from the chloro precursor 4 that bears sterically bulky substituents at the phosphorus centers. On the other hand, the optically pure trichiral complex 6 that bears sterically less bulky substituents at the phosphorus gives a mixture of two diastereomers (11a and 11b). Protonation of complex 7 using different acids (HX) gives a mixture of [(eta5-Cp)Ru(eta2-H2){kappa 2-P,P-(RO)2PN(Me)P(OR)2}]X (12a) and [(eta5-Cp)Ru(H)2{kappa2-P,P-(RO) 2PN(Me)P(OR)2}]X (12b) of which 12a is the major product independent of the acid used; the dihydrogen nature of 12a is established by T1 measurements and also by synthesizing the deuteride analogue 7-D followed by protonation to obtain the D-H isotopomer. Preliminary investigations on asymmetric transfer hydrogenation of 2-acetonaphthone in the presence of a series of chiral diphosphazane ligands show that diphosphazanes in which the phosphorus centers are strong pi-acceptor in character and bear sterically bulky substituents impart moderate levels of enantioselectivity. Attempts to identify the hydride intermediate involved in the asymmetric transfer hydrogenation by a model reaction suggests that a complex of the type, [Ru(H)(Cl){kappa2-P,P-X2PN(R)PY2}(sol vent)2] could be the active species in this transformation.

If you are interested in 32993-05-8, you can contact me at any time and look forward to more communication.Application of 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II), molecular formula is C41H35ClP2Ru. In a Article£¬once mentioned of 32993-05-8, Formula: C41H35ClP2Ru

Synthesis and biological assessment of a ruthenium(II) cyclopentadienyl complex in breast cancer cells and on the development of zebrafish embryos

Ruthenium-based complexes currently attract great attention as they hold promise to replace platinum-based drugs as a first line cancer treatment. Whereas ruthenium arene complexes are some of the most studied species for their potential anticancer properties, other types of ruthenium complexes have been overlooked for this purpose. Here, we report the synthesis and characterization of Ru(II) cyclopentadienyl (Cp), Ru(II) cyclooctadienyl (COD) and Ru(III) complexes bearing anastrozole or letrozole ligands, third-generation aromatase inhibitors currently used for the treatment of estrogen receptor positive (ER +) breast cancer. Among these complexes, Ru(II)Cp 2 was the only one that displayed a high stability in DMSO and in cell culture media and consequently, the only complex for which the in vitro and in vivo biological activities were investigated. Unlike anastrozole alone, complex 2 was considerably cytotoxic in vitro (IC50 values < 1 muM) in human ER + breast cancer (T47D and MCF7), triple negative breast cancer (TNBC) (MBA-MB-231), and in adrenocortical carcinoma (H295R) cells. Theoretical (docking simulation) and experimental (aromatase catalytic activity) studies suggested that an interaction between 2 and the aromatase enzyme was not likely to occur and that the bulkiness of the PPh3 ligands could be an important factor preventing the complex to reach the active site of the enzyme. Exposure of zebrafish embryos to complex 2 at concentrations around its in vitro cytotoxicity IC50 value (0.1?1 muM) did not lead to noticeable signs of toxicity over 96 h, making it a suitable candidate for further in vivo investigations. This study confirms the potential of Ru(II)Cp complexes for breasts cancer therapy, more specifically against TNBCs that are usually not responsive to currently used chemotherapeutic agents. Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Formula: C41H35ClP2Ru. In my other articles, you can also check out more blogs about 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 32993-05-8. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 32993-05-8, Name is Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II)

Access to novel fluorovinylidene ligands via exploitation of outer-sphere electrophilic fluorination: New insights into C-F bond formation and activation

Metal vinylidene complexes are widely encountered, or postulated, as intermediates in a range of important metal-mediated transformations of alkynes. However, fluorovinylidene complexes have rarely been described and their reactivity is largely unexplored. By making use of the novel outer-sphere electrophilic fluorination (OSEF) strategy we have developed a rapid, robust and convenient method for the preparation of fluorovinylidene and trifluoromethylvinylidene ruthenium complexes from non-fluorinated alkynes. Spectroscopic investigations (NMR and UV/Vis), coupled with TD-DFT studies, show that fluorine incorporation results in significant changes to the electronic structure of the vinylidene ligand. The reactivity of fluorovinylidene complexes shows many similarities to non-fluorinated analogues, but also some interesting differences, including a propensity to undergo unexpected C-F bond cleavage reactions. Heating fluorovinylidene complex [Ru(eta5-C5H5)(PPh3)2(CC{F}R)][BF4] led to C-H activation of a PPh3 ligand to form an orthometallated fluorovinylphosphonium ligand. Reaction with pyridine led to nucleophilic attack at the metal-bound carbon atom of the vinylidene to form a vinyl pyridinium species, which undergoes both C-H and C-F activation to give a novel pyridylidene complex. Addition of water, in the presence of chloride, leads to anti-Markovnikov hydration of a fluorovinylidene complex to form an alpha-fluoroaldehyde, which slowly rearranges to its acyl fluoride isomer. Therefore, fluorovinylidenes ligands may be viewed as synthetic equivalents of 1-fluoroalkynes providing access to reactivity not possible by other routes.

If you are hungry for even more, make sure to check my other article about 32993-05-8. Application of 32993-05-8

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 14564-35-3, Name is Dichlorodicarbonylbis(triphenylphosphine)ruthenium(II), molecular formula is C38H34Cl2O2P2Ru. In a Article£¬once mentioned of 14564-35-3, COA of Formula: C38H34Cl2O2P2Ru

HOMOGENEOUS HYDROGENATION OF ALDEHYDES TO ALCOHOLS WITH RUTHENIUM COMPLEX CATALYSTS

A number of ruthenium complexes catalyse the reduction of aldehydes to their corresponding alcohols in toluene solution under mild reaction conditions.The most convenient catalyst precursor is hydridochlorocarbonyltris(triphenylphosphine)ruthenium(II).Turnover numbers up to 32 000 have been achieved with this catalyst.The rate of hydrogenation is first order with respect to the substrate concentration, the catalyst concentration and the hydrogen pressure, and is also affected by acid and basic additives.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.COA of Formula: C38H34Cl2O2P2Ru. In my other articles, you can also check out more blogs about 14564-35-3

Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI