M.W:800-900| Page 122 of 132 | Ruthenium catalysts

The important role of (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

With the complex challenges of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

Name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 246047-72-3, its synthesis route is as follows.,246047-72-3

After a 50 mL two-necked flask was purged with argon, the ligand 3cw (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate after filtration to obtain sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 4cw, yield: 85%.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Downstream synthetic route of (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO206,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Analyzing the synthesis route of 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Some tips on (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

With the complex challenges of chemical substances, we look forward to future research findings about 246047-72-3,belong ruthenium-catalysts compound

As a common heterocyclic compound, it belongs to ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, and cas is 246047-72-3, its synthesis route is as follows.,246047-72-3

To a solution of 13a (22.0 mg, 0.038 mmol) in anhydrous CH2Cl2 (5.0 ml) was added2nd generation Grubbs catalyst (29.0 mg, 0.034 mmol) and CuCl (I) (7.5 mg, 0.075mmol) under nitrogen at 30 C and stirred for 3 h. The reaction mixture wasconcentrated in vacuo, and the residue was purified by column chromatography onsilica gel (hexane / CH2Cl2 = 1 / 1) to give 3a (14.0 mg, 35%).Green crystals; mp 178-183 C (dec.); 1H NMR (270 MHz, CDCl3) delta 2.09-2.00 (m, 2H),2.43 (d, J = 14.0 Hz, 18H), 2.86 (t, J = 12.1 Hz, 2H), 4.17 (s, 4H), 4.27 (t, J = 10.2 Hz,2H), 6.91 (s, 1H), 7.08 (s, 4H), 7.43 (s, 1H), 16.32 (s, 1H); 19F NMR (466 MHz, CDCl3)delta -80.5 (3F), -109.2 (2F), -121.0 (2F), -121.3 (2F), -121.7 (4F), -122.5 (2F), -126.0(2F); 13C NMR (68 MHz, CDCl3) delta 19.2, 21.0, 22.1, 23.6, 51.7, 70.2, 118.0, 123.3,124.2, 127.1, 129.6, 136.1, 138.7, 139.0, 142.8, 143.2, 151.8, 209.2, 288.5; IR (FT)3979, 3857, 3747, 3685, 3417, 2956, 2918, 2363, 2336, 1596, 1481, 1413, 1240, 1208,1140, 1046, 988, 904, 857, 809, 741, 720 cm-1; HRMS (FAB) m/z [M+H]+ calcd forC39H36Cl2F17N2ORu 1044.0977; found 1044.0991.

With the complex challenges of chemical substances, we look forward to future research findings about 246047-72-3,belong ruthenium-catalysts compound

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

The important role of 246047-72-3

A 50 mL two-necked flask was purged with argon and then the ligand 7q (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After completion of the reaction, silica gel was added to the filtrate after filtration, and the crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain a green solid product 8q. Yield: 59%.

The important role of 246047-72-3

To a dry 100 mL round-bottom flask containing a magnetic stirbar, under argon, was added 1.79 g (2.1 mmol, 1.0 equiv) [5], CuCl (521 mg, 5.28 mmol, 2.51 equiv), and 25 mL of anhydrous CH2Cl2. Ligand precursor [2] (403 mg, 2.1 mmol, 1.0 equiv) was added to the reddish solution in 20 mL of CH2Cl2 at room temperature. A reflux condenser was added and the mixture was heated for 70 minutes, under argon. The crude product was concentrated and loaded onto silica gel and eluted with 2:1 pentane:CH2Cl2 then 1:1 pentane:CH2Cl2 to remove a dark green band. The column was washed with CH2Cl2, then Et2O. The green and yellow bands were combined and concentrated under reduced pressure to yield a dark green solid. The solvents are removed under reduced pressure and the solid was crystallized from hexane to yield 1.07 g (1.70 mmol, 85%) of [6]. 1H NMR (300 MHz, CDCl3) delta: 16.56 (s, 1H, Ru=CHAr), 7.48 (m, 1H, aromatic CH), 7.07 (s, 4H, mesityl aromatic CH), 6.93 (dd, J=7.4 Hz, 1.6 Hz, 1H, aromatic CH), 6.85 (dd, J=7.4 Hz, 1H, aromatic CH), 6.79 (d, J=8.6 Hz, 1H, aromatic CH) 4.90 (septet, J=6.3 Hz, 1H, (CH3)2CHOAr), 4.18 (s, 4H, N(CH2)2N), 2.48 (s, 12H, mesityl o-CH3), 2.40 (s, 6H, mesityl p-CH3), 1.27 (d, J=5.9 Hz, 6H, (CH3)2CHOAr. 13C NMR (75 MHz, CDCl3) delta: 296.8 (q, J=61.5 Hz), 211.1, 152.0, 145.1, 145.09, 138.61, 129.4 (d, JNC 3.9 Hz), 129.3, 129.2, 122.6, 122.1, 122.8, 74.9 (d, JOC 10.7 Hz), 51.4, 30.9, 25.9, 21.01.

Reference£º
Patent; MATERIA, INC.; Pederson, Richard L.; Woertink, Jason K.; Haar, Christopher M.; Gindelberger, David E.; Schrodi, Yann; (13 pag.)US9504997; (2016); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Downstream synthetic route of (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

With the synthetic route has been constantly updated, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO367,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

A suspension of 500 mg (0.59 mmol) of [RuCl2(PCy3) (ImH2Mes)(phenylmethy- lene)] (commercially available from Sigma-Aldrich Inc., St. Louis, USA), 60 mg (0.61 mmol) copper chloride and 100 mg (0.64 mmol) 8-vinylquinoline (prepared according to G.T. Crisp, S. Papadopoulos, Aust. J. Chem. 1989, 42, 279-285) in 40 ml methylene chloride was stirred at room temperature for 90 min. The reaction mixture was evaporated to dryness and the isolated crude product purified by silica gel chromatography (hexane / ethyl acetat 2:1) to yield 255 mg (70%) of the title compound as green crystals. MS: 584.4 (M-Cl+). 1H-NMR (300 MHz, CD2Cl2): 2.36 (s, 6H); 2.40 (s, 12H); 4.04 (s, 4H); 7.01 (s, 4H); 7.19 (dd, J=8.4, 4.9Hz, IH); 7.34 (t, J=7.7Hz, IH); 7.51 (d, J=7.1Hz, IH); 8.08-8.18 (m, 2H); 8.26 (dd, J=4.8, 1.3Hz, IH); 16.95 (s, IH). Anal, calcd. for C3IH33N3Cl2Ru: C, 60.09; H, 5.37; N, 6.78; Cl, 11.44. Found: C, 60.06; H, 5.75; N, 6.16; Cl, 10.90.

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/644; (2008); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

New learning discoveries about 246047-72-3

246047-72-3, 246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

After a 50 mL two-necked flask was replaced with argon, the ligands 3bx (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was completed, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain 4bx as a green solid, yield: 65%.

Share a compound : 246047-72-3

246047-72-3 is used more and more widely, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,246047-72-3

Example 1Synthesis of Ru complex 4a (H2IMes)(PCy3)Cl2Ru=CHPh (formula lb, 860mg, l .Ommol) and CuCl (270 mg, 2.5mmol, 2.5 eq) were added into a 100 mL of two-neck round-bottom flask filled with inert gas (Ar), and followed by adding DCM (15 mL) and ligand 3a (250 mg, 1.2mmol, 1.2 eq) into the DCM solution at 20-25C. The reaction was stirred until completed in 30-60 min. (monitored by TLC). The reaction mixture was filtered and concentrated, then purified by flash column eluting with a gradient solvent (Pentane/DCM 2/1 to DCM). The purified solid product was washed with methanol, and dried under vacuum to obtain 27mg of green solid product 4a, yield: 4%. The green product was confirmed by 1HNMR. Ru complex (4a) 1HNMR (400 MHz, CDC13): delta 19.09 (s, lH, Ru=CH),7.51-6.70 (m, 13H), 5.31 (m, 1H), 4.30 (d, J = 12.9 Hz, 1H), 4.04 (s, 4H, NCH2CH2N), 3.61 (d, J= 12.9 Hz, 1H), 2.45 (s, 12H), 2.33 (s, 6H).; Example 9 Synthesis of Ru complex 4j The synthetic procedure is the same as in Example 1 in 1.0 mmol scale. 353 mg of green solid product 4j was obtained (yield: 48%). Ru complex (4j) 1H- MR (400 MHz, CDC13): delta 18.88 (s, lH, Ru=CH), 7.57-6.44 (m, 11H), 5.36 (t, J = 13.2 Hz, 1H), 4.16-4.02 (m, 5H), 4.01 (d, J = 13.2 Hz, 1H), 2.75-2.00 (m, 19H), 1.01-0.90 (m, 6H).

Reference£º
Patent; ZANNAN SCITECH CO., LTD.; ZHAN, James Zheng-Yun; WO2011/79439; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Some tips on 246047-72-3

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

To a 40 mL scintillation vial equipped with a magnetic stir bar was added C848 (0.500 g, 0.589 mmol), ^-toluenesulfonyl chloride (0.056 g, 0.30 mmol), tetrahydrothiophene 1- oxide (0.307 g, 2.94 mmol), and dichloromethane (4 mL). The reaction was stirred at ambient temperature for one hour then diluted with diethyl ether (25 mL). The precipitate was isolated by filtration, washed with diethyl ether (2 x 10 mL) followed by hexanes (1 x 15 mL) then dried in vacuum to afford C673 (0.248 g, 62.6% yield). [000131] 1H MR (400 MHz, CDCh) delta 16.12 (s, 1H), 7.82 (d, J = 7.7 Hz, 2H), 7.55 (t, J = 7.2 Hz, 1H), 7.23 (t, J = 7.7 Hz, 2H), 7.11 (br s, 2H), 6.93 (s, 1H), 6.29 (s, 1H), 4.11 – 3.94 (m, 3H), 3.86 – 3.76 (m, 1H), 2.72 (s, 3H), 2.69 (s, 3H), 2.64 (s, 3H), 2.62 – 2.45 (m, 3H), 2.35 (s, 3H), 2.27 – 2.17 (m, 1H), 2.15 (s, 3H), 2.07 (s, 3H), 2.05 – 1.91 (m, 2H), 1.84 – 1.68 (m, 2H)., 246047-72-3

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; MATERIA, INC.; JOHNS, Adam, M.; (112 pag.)WO2018/38928; (2018); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI