Tag: M.W:900-1000

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

General procedure: Diphosphine ligand (2.0 mmol) was dissolved in 10 mL of dichloromethane and the solution was added dropwise to a stirred solution of RuCl2(PPh3)3 (1.0 mmol) in 10 mL of dichloromethane. The reaction mixture was stirred approximately for 50 min at room temperature. The brown solution was filtered to remove the insoluble impurities. The solvent was reduced by a vacuum and the product was then precipitated by adding n-hexane. The yellow solid was filtered and washed three times with 20 mL of diethyl ether.

15529-49-4 is used more and more widely, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II)

Reference£º
Article; Al-Noaimi, Mousa; Warad, Ismail; Abdel-Rahman, Obadah S.; Awwadi, Firas F.; Haddad, Salim F.; Hadda, Taibi B.; Polyhedron; vol. 62; (2013); p. 110 – 119;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

General procedure: Diphosphine ligand (2.0 mmol) was dissolved in 10 mL of dichloromethane and the solution was added dropwise to a stirred solution of RuCl2(PPh3)3 (1.0 mmol) in 10 mL of dichloromethane. The reaction mixture was stirred approximately for 50 min at room temperature. The brown solution was filtered to remove the insoluble impurities. The solvent was reduced by a vacuum and the product was then precipitated by adding n-hexane. The yellow solid was filtered and washed three times with 20 mL of diethyl ether., 15529-49-4

15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Article; Al-Noaimi, Mousa; Warad, Ismail; Abdel-Rahman, Obadah S.; Awwadi, Firas F.; Haddad, Salim F.; Hadda, Taibi B.; Polyhedron; vol. 62; (2013); p. 110 – 119;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

To [RuCl2(PPh3)3] (360 mg, 0.375 mmol) was added a solution of la (100 mg, 0.375 mmol) in 5 ml of CH2C12 with stirring. The resulting burgundy solution was stirred at room temperature. An analysis of the reaction mixture by 31 P NMR spectroscopy after 1 hour revealed complete conversion of the starting material into the product, indicated by a resonance at delta 40.9 ppm, and the presence of free PPh3, delta -5.5 ppm). After reacting for a total of 2 hours, the burgundy solution was concentrated to approximately 40% of its original volume, followed by layering with diethyl ether (22 ml). After six days, the mother liquor was decanted, leaving a light pink powder. This powder was transferred to a filter frit, washed with diethyl ether (3 x 10 ml) and vacuum dried overnight. Isolated yield of complex A-l : 236 mg (90%). Elem. Anal: Calc’d for (0418) C32H37Ci2N2OPRuS (700.66): C, 54.86; H, 5.32; N, 4.00%. Found: C, 54.96; H, 5.19; N, 4.03%. 31P{1H} (162 MHz, CD2C12, r.t.): delta 41.0 (s). 1H NMR (400 MHz, CD2C12, r.t.): delta 2.81 (vt, J~ 14 Hz, 1H), 2.93-3.07 (m, 2H), 3.16-3.39 (m, 7H), 3.46-3.58 (m, 2H), 3.62-3.68 (m, 3H), 3.81 (vt, J~ 13 Hz, 1H), 5.88 (brs, NH, 1Eta), 6.98 (t, J~ 8 Hz, 2H), 7.20-7.33 (m, 12H), 7.72 (vt, J~ 9 Hz, 6H). 13C{1H} (100.5 MHz, CD2C12, r.t.): delta 44.9 (s, 1C), 47.0 (s, 1C), 48.4 (s, 1C), 52.9 (s, 1C), 54.7 (s, 1C), 59.3 (s, 1C), 60.2 (s, 1C), 61.6 (s, 1C), 127.1 (d, JC-P = 8.7 Hz, 6Cmeta, Pi), 127.9 (s, 2Cmeta, Ph), 128.5 (d, JC-P = 1.5 Hz, 3Cpara, PPh3), 128.6 (s, Cpam, Ph), 133.1 (s, (0419) 2Cortho, Ph), 134.5 (d, Jc-P = 9.5 Hz, 6Cortho, Pi), 134.8 (s, 1C^0, Ph), 137.7 (d, J= 36 Hz, ICipso); 31P{1H} (162 MHz, CDC13, r.t.): delta 40.3 (s). 1H NMR (400 MHz, CDC13, r.t.): delta 2.74 (vt, J~ 14 Hz, 1H), 2.94-3.02 (m, 2H), 3.11-3.45 (m, 9H), 3.51-3.70 (m, 5H), 3.78 (vt, J~ 13 Hz, 1H), 5.87 (brs, NH, 1Eta), 6.95 (t, J~ 8 Hz, 2H), 7.15-7.32 (m, 12H), 7.72 (t, J~ 9 Hz, 6H). 13C{1H} (100.5 MHz, CDC13, r.t.): delta 45.2 (s, 1C), 47.2 (s, 1C), 48.5 (s, 1C), 52.8 (s, 1C), 54.8 (s, 1C), 58.9 (s, 1C), 60.2 (s, 1C), 61.6 (s, 1C), 127.3 (d, Jc_P = 8.7 Hz, 6Cmeta, Pi), 128.1 (s, 2Cmeta, Ph), 128.7 (d, Jc-P = 1.5 Hz, 3Cpara, Pi), 128.8 (s, Cpara, Ph), 133.2 (s, 2Cortho, Ph), 134.6 (d, Jc-P = 9.5 Hz, 6Cortho, Pi), 134.5 (s, lCipso, Ph), 137.1 (d, J= 36 Hz, 3Cipso).

As the rapid development of chemical substances, we look forward to future research findings about 15529-49-4

Reference£º
Patent; LOS ALAMOS NATIONAL SECURITY, LLC; DUB, Pavel, A.; GORDON, John, Cameron; WO2015/191505; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A methanol (10ml) solution containing the appropriate N-S pro-ligand and triethylamine was refluxed under argon for 15min and then the complex [RuCl2(PPh3)3] was added. The resulting brown suspension was refluxed for 3h, to afford a yellow suspension. After cooling, the yellow solid was collected by filtration, washed with methanol (3¡Á5ml), and dried under reduced pressure. 2.6.2 [Ru(mcbtz)2(PPh3)2] (2) Hmcbtz (0.035 g – 2.0 * 10-4 mol); NEt3 (30 mul – 2.0 * 10-4 mol), and [RuCl2(PPh3)3] (0.095 g – 9.9 * 10-5 mol). Yield: 65 mg – 68.5%. 31P{1H} NMR (81 MHz, CDCl3) 52.2 ppm (s). 1H NMR (200 MHz, CDCl3), delta/ppm 8.0-6.5 (m, 30H Ph – PPh3 and 8H Ph – mcbtz-). Anal.exp. (calc. for C50H38N2P2RuS4) C-62.3 (62.7); H, 4.0 (4.0); N, 2.8 (2.9); S, 12.8(13.4).

15529-49-4, 15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Article; Appelt, Patricia; Fagundes, Francisco D.; Facchin, Gianella; Gabriela Kramer; Back, Davi F.; Cunha, Mario A.A.; Sandrino, Bianca; Wohnrath, Karen; De Araujo, Marcio P.; Inorganica Chimica Acta; vol. 436; (2015); p. 152 – 158;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

(PPh3)3RuCI2 (1 eq., 0.575 g, 0.6 mmol) and 3-(2,3-dimethoxy-5-(methoxymethyl)phenyl)- 4,4-dimethylpent-1-yn-3-ol (1.5 eq., 0.263 g, 0.9 mmol) were added in 4 ml HClldioxane solution (0.15 molIl). The solution was heated to 90C for 3 hour, after which the solvent was removed under vacuum. Hexane (20 ml) was added to the flask and the solid was ultrasonically removed from the wall. The resulting suspension was filtered and washed two times using hexane (5 ml). The remaining solvent was evaporated affording a orange powder; 0.31 g (Yield: 80 %). The product was characterized by NMR spectra 31P.31P NMR (121.49 MHz, CDCI3): 652.09.

As the rapid development of chemical substances, we look forward to future research findings about 15529-49-4

Reference£º
Patent; GUANG MING INNOVATION COMPANY (WUHAN); W.C. VERPOORT, Francis; YU, Baoyi; WO2014/108071; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

General procedure: To a round-bottomed flask with a stir bar was placed with [Ru(PPh3)3Cl2] (868 mg, 2.0 mmol) under the nitrogen. Pre-dried THF(10 mL) was added and the resulting mixture was stirred at room temperature. Then salen-enH2 (536 mg, 2.0 mmol) and a little excess of Et3N (252 mg, 2.5 mmol) in THF (5 mL) were added. The reaction mixture was stirred at room temperature overnight. After removal of solvents, CH2Cl2 (15 mL) was added and the solution was filtered through cilite. The filtrate was concentrated and the residue was washed with Et2O (5mL 2) and hexane (5 mL 2) to give the desired product. Recrystallization from CH2Cl2/Et2O (1:2) afforded green block-shaped crystals of [RuCl(PPh3)(salen)] (3) suitable for X-ray diffraction in three days. Yield: 1011 mg, 76% (based on Ru).

As the rapid development of chemical substances, we look forward to future research findings about 15529-49-4

Reference£º
Article; Tang, Li-Hua; Wu, Fule; Lin, Hui; Jia, Ai-Quan; Zhang, Qian-Feng; Inorganica Chimica Acta; vol. 477; (2018); p. 212 – 218;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

15529-49-4, Compound 5 (300.0 mg, 0.68 mmol) and degassed morpholine (10 mL) were placed in a 100-mL Young-Schlenk container substituted with argon gas. Thereafter, the Young-Schlenk container was placed in an oil bath, and heated to 120 C. while stirring the components in the Young-Schlenk container, thereby causing a reaction. The progress of the reaction was confirmed by thin-layer chromatography (TLC), and the heating was stopped after two hours. Subsequently, the morpholine in the reaction mixture restored to room temperature (25 C.) was removed after collection with a liquid nitrogen trap under reduced pressure (0.1 to 2 mmHg). At this time, the reaction mixture was sufficiently stirred, and the Young-Schlenk container was immersed in water at room temperature (25 C.) to prevent cooling of the Young-Schlenk container by the heat of vaporization. After sufficiently removing the morpholine, dichlorotris(triphenylphosphino)ruthenium (II) (648.6 mg, 0.68 mmol) and dehydrated toluene (15 mL) were added while introducing argon gas into the container, and the mixture was heated to 110 C. using an oil bath, thereby causing a reaction. The heating was stopped after two hours, and the reaction mixture was restored to room temperature (25 C.). Subsequently, dehydrated hexane (40 mL) was added to the reaction mixture in an argon gas atmosphere. Thereafter, the whole mixture, including the hexane layer and the toluene layer, in the Young-Schlenk container was stirred and completely mixed. After leaving the mixture unattended for an hour, the generated purple substance was filtered out in an argon atmosphere while being washed with dehydrated diethylether, thereby obtaining a crude product. Subsequently, the resulting crude product was subjected to column chromatography (developing solvent: chloroform/ethyl acetate=5/1) in which silica gels are accumulated to about 10 cm, thereby removing a compound with high polarity. The effluent was collected to a flask and the collection was continued until the color of the purple liquid was slightly diluted. After this operation, the solution collected in the recovery flask was rapidly concentrated by an evaporator, thereby obtaining 204.3 mg (0.35 mmol, 51%)of substantially pure Compound 2b (RUPIP2) as a purple substance. The spectral data of Compound 2b (RUPIP2) is shown below. 1H NMR (600 MHz, CDCl3): delta 7.89 (d, 2H, J=8.3 Hz, C10H6N2), 7.69 (t, 2H, J=7.6 Hz, C10H6N2), 7.59 (d, 2H, J=8.3 Hz, C10H6N2), 3.89 (d, 4H, J=7.6 Hz, PCH2), 2.67-2.78 (m, 4H, CH(CH3)2), 1.35-1.43 (m, 24H, CH(CH3)2). 13C NMR (151 MHz, CDCl3): delta 163.3, 158.3, 134.4, 121.9, 120.0, 42.1 (d, 1JPC=20.2 Hz), 25.4, 20.5, 19.4. 31P{1H} NMR (243 MHz, CDCl3): delta 60.6. HRMS (ESI, (M-Cl)+) Calcd for C24H38ClN2P2Ru+: 553.1242. Found m/z=553.1240.

As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Patent; National University Corporation Nagoya University; Saito, Susumu; Noyori, Ryoji; Miura, Takashi; Naruto, Masayuki; Iida, Kazuki; Takada, Yuki; Toda, Katsuaki; Nimura, Sota; Agrawal, Santosh; Lee, Sunkook; (42 pag.)US9463451; (2016); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

Wilkinson prepared cis-RuCl2(PPh3)2(NCPh)2 by the reaction of RuCl2(PPh3)3 with NCPh in acetone and characterized it by elemental analysis and infrared spectroscopy [1]. In our hands this compound can also be obtained by the reaction in toluene. A 0.099 g (0.10 mmol) sample of RuCl2(PPh3)3 was added to 0.032 mL (0.033 g, 0.32 mmol) of NCPh in 2 mL toluene. The resulting mixture was stirred rapidly for several seconds and immediately filtered. After 3-6 h at room temperature yellow crystals began to form. After about 24 h the supernatant was removed and the yellow crystalline RuCl2(PPh3)2(NCPh)2 was dried under vacuum to yield 0.093 g (0.10 mmol, 100%) of RuCl2(PPh3)2(C7H5N)2, m.p. = 186.5-187.9 C (dec), IR(KBr (cm-1): 3052 m, 2240 m, 2230 m, 2216 m, 1431 s, 1259 w, 1085 m, 1023 w, 740 s, 692 s, 512. 31P NMR (CDCl3): 25.6 s. X-ray quality crystals were obtained from a similar reaction that took place in an NMR tube in d-toluene.

With the rapid development of chemical substances, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II)

Reference£º
Article; Cruz, Santina S.; Amenta, Donna S.; Gilje, John W.; Yap, Glenn P.A.; Polyhedron; vol. 114; (2016); p. 179 – 183;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

A mixture of HL1 (80mg, 0.20mmol), triethylamine (20mg, 0.20mmol) and 1[Ru(PPh3)3Cl2] (192mg, 0.20mmol) were stirred in tetrahydrofuran (20mL) for 6h at room temperature, during which the color of solution changed from brown to dark red. After removal of solvents in vacuo, dichloromethane (20mL) was added and the solution was filtered. The filtrate was concentrated and the residue was washed with diethyl ether (5mL¡Á2) and hexane (5mL¡Á2) to give the desired product. Recrystallization from dichloromethane/hexane (1:3) afforded dark red block crystals of [Ru(L1)(PPh3)2Cl] (1) suitable for X-ray diffraction in three days. Yield: 140mg, 66% (based on ruthenium). IR (KBr disc, cm-1): nuC=N 1568 (m), nuC-O 1304 (s), nuC-S 744 (w), nuPPh3 1433(m), 1091(s) and 694 (w), nuC-Br 564 and 529 (s); 31P NMR (CDCl3, 162MHz): delta 17.0 (s, PPh3) ppm. 1H NMR (CDCl3, 400MHz): delta 9.82 (s, 1H, CH=N), 7.91-7.52 (m, 30H, PPh3), 7.21-7.10 (m, 2H, Ar-H), 6.35-6.20 (m, 4H, Ar-H), 2.17 (s, 3H, SCH3) ppm. MS (FAB): m/z 1061 [M+], 1026 [M+-Cl], 799 [M+-PPh3], 537 [M+-2PPh3], 513 [Ru(L1)]+. Anal. Calc. for C50H40NOP2ClBr2SRu: C, 56.59; H, 3.80; N, 1.32%. Found: C, 56.54; H, 3.83; N, 1.36%.

As the rapid development of chemical substances, we look forward to future research findings about 15529-49-4

Reference£º
Article; Ji, Jiao; Chen, Xin; Lin, Hui; Jia, Ai-Quan; Zhang, Qian-Feng; Inorganica Chimica Acta; vol. 494; (2019); p. 105 – 111;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

Example 9: Dichloro[2-(diphenylphosphino)-N-(2-(methylthio)benzyl)ethanamine]ruthenium(ll) (9) Under argon NaBH4 (0.13 g, 3.47 mmol) is added to a solution of 2-(diphenylphosphino)-N- (2-(methylthio)benzylidene)ethanamine (0.42 g, 1.16 mmol) in ethanol (7 ml). After stirring for 20 h at 80 C the reaction mixture is cooled to room temperature and DCM (10 ml) is added, followed by saturated aqueous NH4Cl-solution. The phases were separated and 5 the organic phase is washed twice with water and once with brine. The organic phase is dried over MgSO4, filtered and concentrated under vacuo. Ligand 2-(diphenylphosphino)- N-(2-(methylthio)benzyl)ethanamine is obtained as a yellow liquid (0.36 g, 86%). Analytical data: 1H-NMR (400 MHz, CDCl3): 7.76 (m, 1H), 7.44 (m, 4H), 7.34 (m, 6H), 7.24 (m, 2H), 7.12 (m, 1H), 3.86 (s, 2H), 2.81 (m, 2H), 2.49 (s, 3H), 2.34 (m, 2H), 1.75 (bs, 1H). 13C-NMR (400 MHz, CDCl3): 138.89, 138.25, 137.70, 133.13, 129.29, 128.95, 128.82, 128.05, 126.09, 125.31, 51.88, 46.43, 29.48, 16.17. 31P-NMR (500 MHz, CDCl3): -20.60 (s, IP). GC/MS: 350 (16%, [M-15]+), 318 (40%), 200 (26%), 183 (32%), 166 (11%), 152 (19%), 137 (100%), 121 (33%), 15 108 (36%), 91 (25%), 77 (13%), 45 (28%). Under argon dichlorotris(triphenylphosphine)ruthenium(ll) (0.94 g, 0.99 mmol) is added to a solution of 2-(diphenylphosphino)-N-(2-(methylthio)benzyl)ethanamine (0.36 g, 0.99 mmol) in toluene (20 ml). After stirring for 19 h at 110 C the reaction mixture is cooled to room temperature and evaporated under vacuo to a volume of 5 ml. To this suspension 20 hexane (20 ml) is added. After stirring for 15 min the suspension is filtered and washed with hexane (4 ml) and diethyl ether (2 x 4 ml). The light-brown filter cake is dried under vacuo for 19 h and then suspended in diethyl ether (5 ml). After stirring for 15 min the suspension is filtered, washed with diethyl ether (3 x 1 ml) and the filter cake is dried under vacuo. Complex 9 is obtained as a light-brown solid (0.76 g, 96%). Analytical data: 1H-NMR (400 MHz, CDCl3): 7.80 (m, 6H), 7.69 (m, 1H), 7.47 (m, 3H), 7.31-7.01 (m, 17H), 6.88 (dt, 7=2.02, 7.58, 1H), 7.18 (d, 7=7.33, 1H), 5.48 (bs, 1H), 5.23 (d, 7=12.63, 1H), 4.11 (m, 1H), 3.89 (m, 1H), 3.00 (m, 1H), 2.07 (m, 1H), 1.12 (m, 1H), 1.08 (s, 3H). 31P-NMR (500 M Hz, CDCl3): 49.83 (d, 7=27.74, 1P), 37.96 (d, 7=27.74, 1P). Anal, calcd. for C40H39Cl2NP2R11S: C, 60.07 %; H, 4.92 %; N, 1.75 %. Found : C, 60.36 %; H, 4.79 %; N, 1.47 %., 15529-49-4

The synthetic route of 15529-49-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; GIVAUDAN SA; GEISSER, Roger Wilhelm; OETIKER, Juerg Daniel; SCHROeDER, Fridtjof; WO2015/110515; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI